早年衰老综合症(Hutchinson-Gilford Progeria syndrome),简称早衰症。1886年Hutchinson首例报道,1897年Guilford进一步描述,所以也称Hutchinson-Gilford综合征.后来文献中称为HGPS.流行病学调查显示,美国本病的发病率为1/800万,男女之比为1.5:1,97%为白色人种.早衰症是一种极端罕见的先天遗传性疾病,其患者身体的老化过程...
疾病英文名:Hutchinson Gilford progeria syndrome 别名:progeria 患病率:<1 / 1 000 000 遗传方式:常染色体显性 病因 Progeria(早老症)患者在儿童时期会有提早老化的现象发生,又称为Hutchinson - Gilford progeria syndrome。早老症最早是在1886年发现的,但一百...
Synonyms Laminopathies; Progeria Definition Hutchinson-Gilford progeria syndrome (HGPS), often referred to as progeria, is an extremely rare autosomal dominant neonatal condition. Children with HGPS have a small stature, distinctive facial features and rapid aging in many organ systems. Progeria is a...
Progeria(Hutchinson-Gilford Syndrome)早衰症 Othernames:-Hutchinson–Gilfordprogeriasyndrome,Hutchinson–Gilfordsyndrome Definition:Hutchinson-Gilfordprogeriasyndromeisagenetic conditioncharacterizedbythedramatic,rapidappearanceofagingbeginninginchildhood.Affectedchildrentypicallylooknormalatbirthandinearlyinfancy,but...
机译:Hutchinson-Gilford Progeria综合征和骨肉瘤的长期存活患者:案例报告 7. Progeria of stem cells: stem cell exhaustion in Hutchinson-Gilford progeria syndrome [O] . Julius Halaschek-wiener, Angela Brooks-wilson 2007 机译:干细胞早衰:Hutchinson-Gilford早衰综合征的干细胞衰竭 获取原文意见...
1、Other names :- HutchinsonGilford progeria syndrome, HutchinsonGilford syndromeDefinition:Hutchinson-Gilford progeria syndrome is a genetic condition characterized by the dramatic, rapid appearance of aging beginning in childhood. Affected children typically look normal at birth and in early infancy, 2、...
Hutchinson-Gilford progeria syndrome (HGPS) is a rare but well known entity characterized by extreme short stature, low body weight, early loss of hair, lipodystrophy, scleroderma, decreased joint mobility, osteolysis, and facial features that resemble aged persons. Cardiovascular compromise leads to ...
Objective: Hutchinson-Gilford progeria syndrome (HGPS) is a rare early-onset accelerated senescence syndrome. In HGPS, a recently identified de novo dominant mutation of the lamin A gene (LMNA) produces abnormal lamin A, resulting in compromised nuclear membrane integrity. Clinical features include...
Hereditary epidermolysis bullosa 遗传性表皮分解性水疱症 Hutchinson Gilford progeria syndrome 早老症 ... www.deanswer.com|基于41个网页 2. 早衰症候群 ...纪,而是跟同学仔一样,是 12岁女孩子,只因她患了早衰症候群( Hutchinson Gilford Progeria Syndrome)。stinglife.pixnet.net|基于2个网页 3. 早年衰老...
Hutchinson–Gilford progeria syndromeInduced pluripotent stem cellsMechanotransductionSenescenceStem cellsVascular agingHutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a de novo genetic mutation that leads to the accumulation of a splicing isoform of lamin A termed pro...