Akkina R. New generation humanized mice for virus research: comparative aspects and future prospects. Virology. 2013;435:14–28.Akkina R. New generation humanized mice for virus research: comparative aspects and future prospects. Virology. 2013;435(1):14–28. Central...
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More advanced models for immuno-oncology research are also now available. The Taconic hIL-6 NOG mouse displays higher macrophage and monocyte populations than the huNOG-EXL mouse, while hIL-15 NOG and hIL-2 NOG mice support NK cell reconstitution. These models are, however, relatively new and...
The development of humanized mice with functional human immune systems (generated by the engraftment of human lymphoid tissues, HSCs or peripheral blood mononuclear cells) provides an opportunity to carry out translational research on human immunity and autoimmune diseases, and for the study of the bio...
Humanized immune system models utilize advanced techniques to transplant human immune cells or precursor cells into mice. This results in the reconstruction of the human immune system within the mouse. Our company offers two primary models: the PBMC model and the CD34+ HSC model. ...
Thus, humanized mice, defined as mice with human immune system, have become an emerging model to study human cancers. Humanized mouse models have been used for various areas of cancer research including adoptive transfer of chimeric antigen receptor (CAR)-modified T cells, neoantigen vaccination to...
R. (2013). Humanized mice: novel model for studying mechanisms of human immune-based therapies. Immunologic Research, 57(1-3), 326-334.Gonzalez, L, Strbo, N, Podack, ER (2013) Humanized mice: novel model for studying mechanisms of human immune-based therapies. Immunologic Research 57: ...
ThehumanizedCYP2C9 and MRP2 mice are available as part of a larger programofhumanizedandknockout models for xenoreceptors, drug metabolising [...] tipschina.gov.cn tipschina.gov.cn 人源化CYP2C9和MRP2小鼠是一个针对异物受体、药物代谢酶与药物转运体人源化和基因剔除模型的更大规模计划的一部分。
Twitter Google Share on Facebook (redirected fromhumanized) Thesaurus Medical Related to humanized:Humanized monoclonal antibody hu·man·ize (hyo͞o′mə-nīz′) tr.v.hu·man·ized,hu·man·iz·ing,hu·man·iz·es 1.To portray or endow with human characteristics or attributes; make human...