Human programmed cell death 1 receptor (PD1)来源宿主 提供的抗PD-1(派姆单抗),人源化抗体Anti-PD-1 (Pembrolizumab), humanized Antibody产品,该来源宿主查看产品说明书。反应性 Human保存建议 艾美捷提供的抗PD-1(派姆单抗),人源化抗体产品,请将该产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融。其他...
The present invention relates to the biomedicine field, in particular to an anti-human PD-1 humanized monoclonal antibody and its applications. The invention obtains an anti-human PD-1 humanized monoclonal antibody with good specificity, high affinity and stability by screening, and the antibody can...
In PBMC-humanized mouse model (PBMCs from healthy donors), the administration of human monoclonal antibody anti-CAIX, combined with IL-2 could inhibit the progression of renal cell carcinoma via inducing human NK and T cells responses [98]. Anti-tumor activity of nivolumab, atezolizumab, ...
The invention provides an anti-CTLA4 antibody which inhibits the binding of CTLA4 to human B7, in particular, it inhibits binding of CTLA4 to human B7.1 and/or human B7.2. Specific antibodies are provided with specific variable region sequences as well as compositions comprising such antibodies ...
RC48 is a novel recombinant human anti-HER2 monoclonal antibody conjugated with a microtubule inhibitor (MMAE) via a cleavable linker, which can effectively kill HER2-positive tumors as well as tumors with low or heterogeneous HER2 expression through the bystander effect. The purpose of this study...
Labeling of anti-α4β7 antibody (Act-1). Act-1 antibody (anti-α 4β 7 antibody) was obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: α 4β 7 monoclonal antibody (cat #11718) from Dr. A. A. Ansari. The Act-1 antibody...
In another preferred embodiment, the antibody is a monoclonal antibody. In a fourth aspect of the invention, a recombinant protein is provided, which has: (I) the scFv according to the first aspect of the invention, or the antibody according to the third aspect of the invention; ...
Therefore, the transplantation of the PBMCs may develop plasma cells that secrete effective antipathogen antibodies. If we establish the technology for monoclonal antibody preparation, we may obtain the monoclonal antibody reagents for the treatment of such deleterious infectious diseases. The humanized ...
Keywords: engineered antibody;humanized;HED bodies;breast cancer;IFN-γ
HIS NRG mice have also been used as a platform to create monoclonal IgGs antibodies that can be used for passive immunization against HCMV. Vaccination of HIS NRG mice with dendritic cells expressing GM-CSF, interferon alpha, and an HCMV antigen (gB) generated different anti-gB IgG antibodies...