Sarah Hall's "Mrs Fox" (in Madame Zero, 2017) reflects the short story's potential to explore epistemological borders and to engage in ecocritical discourses. In recounting the transformation of a young woman into a vixen through the...Ditter, Julia...
We observed that highland developments caused considerable ecological land loss and fragmentation. Transforming ecological lands into human use in highlands exhibited higher ecological costs in low and lower-middle-income countries (∼1.9 times the rate of ecological land loss) than in high and upper-...
H. Genetic transformation of mouse embryos by microinjection of purified DNA. Proc. Natl Acad. Sci. USA 77, 7380–7384 (1980). CAS PubMed PubMed Central Google Scholar Brinster, R. L. et al. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into...
This apparent gap between discovery and its transformation into profitable outputs has been clarified in terms of the poor predictiveness of animal models and a lack of scientific rigor that results in a lack of beneficial effect in subsequent clinical trials [3, 15]. The other barriers are ...
The instinct vs conscious intellect explanation of the human condition is actually very obvious, and it shows just how wrong and absurd the old excuse is that ‘we are competitive and aggressive because we have savage animal instincts’! I present a short history of the many thinkers who have...
Zeros in the species and pathway abundance table were replaced by a pseudo-count of 1 × 10−6 and 1 × 10−8 before the log10-transformation. During the training phase, a 10-fold cross-validation strategy was employed to tune the lambda parameter (regulation strength). The ...
An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the rapidly evolving SARS-CoV-2 virus and for development of prophylactic and therapeutic strategies to combat emerging mutants. Studies show that the spike proteins of SARS-CoV and SARS-CoV-2 bind ...
They appear to have a modern foot anatomy and style of locomotion providing new insight into the evolution of human gait. The hominin prints occur in association with a range of animal prints providing information on the faunal community and the paleo-environmental context of the hominins. Here ...
introduced by the nuclease, the lack of toxicity, of abnormal clonal expansion and of oncogenic transformation in animals infused with gene edited WAS HSPCs 26 weeks after transplantation support the overall safety of our approach. Nevertheless, further work to verify absence of genotoxicity in more ...
Birds are among the best-studied animal groups, but their prehistoric diversity is poorly known due to low fossilization potential. Hence, while many human-driven bird extinctions (i.e., extinctions caused directly by human activities such as hunting, as well as indirectly through human-associated...