Secretion and expression levels of immune-related genes were analyzed using ELISA and RT-qPCR techniques. Based on the results, the proliferation potential of OE-MSCs was significantly higher than that of AT-MSCs. The gene expression and also protein levels of both TLR3 and TLR4 were ...
C, IL-6 production in SV40-fibroblasts from patients (P2-P5), a TLR3−/− control, and five healthy controls, as measured by ELISA, in the supernatant of control and patient SV40-fibroblasts stimulated with 25 μg/mL poly(I:C) alone, Lipofectamine alone, or both. TLR3−/− ...
Jensen, L.E. and A.S. Whitehead (2003) Cell. Signal.15:793. Smith, D.E.et al. (2003) Immunity18:87. Long Name Interleukin 1 Receptor Accessory Protein Entrez Gene IDs 3556 (Human); 16180 (Mouse) Alternate Names C3orf13IL-1RAcPIL1R3Interleukin-1 receptor 3; FLJ37788; IL-1 ...
Similar to human GEs at GW20–23, the blood vessel density in the E13.5–17.5 mouse brain was higher in the GEs than in the cortical plate (Extended Data Fig.2a,b). Although vascular branch point density did not differ between the two regions, the density of IBA1+cells was higher in ...
CD141hi DCs were most efficient at TNF-α and CXCL10 production after TLR3 stimulation but produced very little IL-1, IL-6, IL-8, or IL-10. LCs also produced CXCL10. CD14+ DCs were the highest producers of IL-1, IL-6, and IL-10 whereas CD1c+ DCs produced mainly IL-8 and IL...
[29]. We identified 19 proteins which were upregulated before the first TPE treatment or in the control old group, as compared to the young group (Fig.2E). Notably, many of these proteins, including CCL20, CCL25, MIF, TLR3, TLR4, IL-2RA, and IL-16, were gradually downregulated by...
Using TLR agonists, we found that both surface and endocytic TLRs can trigger MAIT cells, in particular viral pathogen-associated molecular patterns. Using murine bone marrow-derived DCs, Le Bourhis et al.37 has previously shown that MAIT cells are not responsive to viral infection. This ...
FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB Mi-Jeong Kim Ji Young Kim Ki-Young Lee Cell & Bioscience (2023) Circulating expression patterns of TL1A and FFAR2 in patients with stable and uns...
IL-10 modulates placental responses to TLR ligands. Am J Reprod Immunol 2009;62: 390–399. 55. Koh YQ, Chan HW, Nitert MD et al. Differential response to lipopolysaccharide by JEG-3 and BeWo human choriocarcinoma cell lines. Eur J Obstet Gynecol Reprod Biol 2014;175:129–133. 438 ...
Using tonsillar cells of allergic patients, it was shown that stimulation of APC via toll-like receptors (TLR) 4 and 8 as well as the cytokines IL-1β and IL-6 have the potential to break specific T cell tolerance towards several environmental allergens1. A similar mechanism is discussed ...