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Overall, the proportion of switch events detected in the cell line data is lower than the one observed in the tissue data (Additional File 2 - Table S12 and Additional File 3 - File S5). Major transcripts do not always code for proteins Functional classification of major transcripts revealed ...
Notably, the effector program of T cells and their expression of immuno-regulatory molecules is closely linked to the function of (APCs), including dendritic cells, macrophages and other monocyte-derived cells14. APCs integrate tissue-specific and inflammation-dependent cues from the tissue environment...
To assess how blood T cells relate to those in tissue, we performed scRNA-seq analysis of resting and activated blood T cells from two adult donors, and projected the merged data onto the UMAP embeddings of T cells from each tissue donor (Fig.2a, b). The majority of blood T cells co-...
Although past studies of gene expression in bulk brain tissue showed major expression changes at the prenatal-to-postnatal transition, it was not possible to determine whether they reflected differences in cell-type-specific transcriptional regulation or changes in cellular composition. Our atlas reveals...
However, these differences are not surprising considering the different tissue origin (brain versus retina) and the transcriptome alterations induced by tumoral transformation. Actually, our developed system may be used to simulate specific cancer cell lines, through the insertion of somatic mutations ...
Monitoring patients with celiac disease on gluten free diet: different outcomes comparing three tissue transglutaminase IgA assays Verification, implementation and harmonization of automated chemiluminescent immunoassays for MPO- and PR3-ANCA detection Performance evaluation of a novel platelet count parameter...
Rat connective tissue growth factor (CTGF) ELISA Kit 大鼠结缔组织生长因子(CTGF)ELISA试剂盒 Humanα-sarcomericactin,α-SCAELISAKit 人α横纹肌肌动蛋白(α-SCA)ELISA试剂盒 96T/48T 分装 HumanAdenovirusAigen,ADV-AgELISA试剂盒人腺病毒抗原(ADV-Ag)ELISA试剂盒规格:96T/48T ...
To probe the diversity of cell types and transcriptional states of cells in localized prostate cancer specimens, we obtained prostate cancer tissue from transrectal prostate biopsies and radical prostatectomy (RP) specimens from men with localized prostate cancer (N = 11 patients, Supplementary Data...
macrophage markers.fSurvival analysis showing thatMMP9 and CTSKhigh expression was associated with worse overall survival (OS) and Disease-specific survival in the TCGA cohorts.gIF staining of MMP9 and CTSK in tissue sections of seminoma patients (n = 3). White arrow represents positive si...