Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. SPK1, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and ...
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Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2). 仅用于科研。不用于诊断过程。未经明确...
(1). S1P is a lipid messenger that regulates diverse physiological processes including cell proliferation, migration, apoptosis, inflammation, calcium homeostasis and cytoskeletal structure (2, 3). The level of S1P is tightly controlled by SPHKs and S1P degrading enzymes. SPHK1 and its activation ...
EDG1/CD363/S1P1 内皮细胞分化鞘脂G蛋白偶联受体1抗体 规格: 0.2ml IL-17B 白介素-17B抗体 规格: 0.1ml EHHADH 三羟酰辅酶A脱酶抗体 规格: 0.2ml Sprouty1 软脂酰化磷蛋白Sprouty1抗体 规格: 0.1ml GIMAP5 GTP酶IMAP家族成员5抗体 规格: 0.2ml JIP1/MAPK8IP1 丝裂原活化蛋白激酶8相互作用蛋白1 规...
The 90 kDa full-length ATF6 is processed within the Golgi to its active 50 kDa form through sequential cleavage by site-1 and site-2 proteases (S1P and S2P). Proteolytic activation of ATF6 in the ER stress response is a mechanism to regulate membrane-bound factors, and is referred to ...
The 90 kDa full-length ATF6 is processed within the Golgi to its active 50 kDa form through sequential cleavage by site-1 and site-2 proteases (S1P and S2P). Proteolytic activation of ATF6 in the ER stress response is a mechanism to regulate membrane-bound factors, and is referred to ...
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