Intranasal administration of recombinant rhinovirus proteinase 2A in mice resulted in an increase in airway hyperreactivity, lung inflammation, and IL-4 and IFN-纬 production from CD4 T cells.Manisha Singh , SeungHyo Lee , Paul Porter , Chuang Xu , Ayako Ohno , ...
Human rhinoviruses (HRVs) comprise by far the largest group, with over 100 serotypes (HRV-1A, HRV-1B and HRV-2 to HRV-100) and will be the exclusive focus for this discussion. There are three bovine rhinoviruses. All are members of Picornaviridae and are classified in the rhinovirus ...
Human rhinovirus (HRV) is the most frequent cause of infection across all age groups of the population [1]. Replication is often restricted to the upper respiratory tract leading to self-limited illnesses such as the common cold. However, HRV infections can also exacerbate pre-existing airway ...
人鼻病毒(Human Rhinovirus)是小 RNA 病毒科、鼻病毒属的一种,是人患普通感 冒的主要病原。鼻病毒抗原性复杂,有 100 多个血清型,感染后可获得免 疫力,但维持时间短,尚无特异预防和 方法。该病毒感染后常表现为感 冒症状,大约有 10%~20%的成年人感 冒是由 HRV 感染引起,而婴幼儿感 冒有15%~30%是由...
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Rhinovirus-induced wheezing in infancy - The first sign of childhood asthma? Although known as common causes of upper respiratory infections, rhinoviruses, enteroviruses, and corona-viruses are poorly studied as inducers of wheezing... Anne Kotaniemi-Syrjnen,Raija Vainionp,TM Reijonen,... - 《...
,Siekierski,and,Stephen,M.摘要: Background: Human rhinovirus (HRV) infections are the predominant cause of the common cold and are associated with exacerbations of asthma. Nitric oxide (NO) may play an important role in host defense by means of its potent antiviral properties. Objective: We...
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Human rhinovirus (HRV) infections are the primary cause of the common cold and are a major trigger for exacerbations of lower airway diseases, such as asthma and chronic obstructive pulmonary diseases. Although human bronchial epithelial cells (HBE) are the natural host for HRV infections, much ...