we carried out differential gene expression analysis between allMLL-AF4infant-ALL (n = 19) andMLL-AF4childhood-ALL (n = 5) samples. We identified 617 significantly differentially expressed genes (false discovery rate (FDR) < 0.05), 193 of which were upregulated inMLL-AF4infant...
Will Carrington, Molly Dahl, and Jimmy Jin of the Health and Human Resources Division—under the supervision of Joseph Kile and David Moore (for- merly of CBO). Matthew Goldberg, Heidi Golding, Rob McClelland, Damien Moore, Carla Tighe Murray, Vi Nguyen, Stephanie...
University of California San Diego (UCSD) Health, University of Iowa, University of California San Francisco (UCSF) Medical Center, Nationwide Children’s Hospital (NCH), or University of Pittsburgh (Pitt) School of Medicine, participants gave verbal and written consent for chart abstraction and uri...
MS-GF+ Kim and Pevzner (2014) http://proteomics.ucsd.edu/software-tools/ms-gf/ Resource availability Lead contact Further information and requests for resources and reagents should be directed to and will be fulfilled by the lead contact, Sebastian Schäfer (sebastian@duke-nus.edu.sg). Materi...
The computations on publicly available data were performed on the Norwegian Research and Education Cloud (NREC), using resources provided by the University of Bergen and the University of Oslo (https://www.nrec.no). All analyses on HRC data were performed using digital laboratories in HUNT Cloud...
Flow cytometry reagents are detailed in the Key Resources Table. Tetramers MHC class I tetramers conjugated to BV421 or PE were used to detect CD8+ T cells with the following specificities: CMV NLVPMVATV (NV9/HLA-A∗0201), HIV FLGKIWPSHK (FK10/HLA-A∗0201), HIV ILKEPVHGV (IV9...
Ethologist Sarah Blaffer Hrdy (1981) has shown that, among our primate cousins, inter-female competition for status and access to resources may seem quieter than the flashy violence of males, but it is also generally more relentless and complex. Darwin's image of females as demure, passive ...
The breadth of information resources available to researchers on the Internet continues to expand, particularly in light of recently implemented data-sharing policies required by funding agencies. However, the nature of dense, multifaceted neuroscience d
Mass spectrometry datasets consisting of raw files and associated peak lists and results files have been deposited in ProteomeXchange through partner Mass spectrometry Interactive Virtual Environment MassIVE (http://proteomics.ucsd.edu/ProteoSAFe/datasets.jsp) as complete submissions. Other files include the...
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein–protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and