To further understand how signalling pathways are activated inVCPmutant microglia we performed a Pathway RespOnsive GENes (PROGENy) analysis[46].VCPmutant microglia displayed activation of hypoxia (NES + 4.88,p = 0.002), JAK-STAT (NES + 4.53,p = 0.002), p53 (NES + 2.7...
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Cameron Church, Christian X. Fay, Emil Kriukov, Hui Liu, Ashley Cannon, Lauren Ashley Baldwin, David K. Crossman, Bruce Korf, Margaret R. Wallace, Andrea M. Gross, Brigitte C. Widemann, Robert A. Kesterson, Petr Baranov & Deeann Wallis ...
E., Cameron, D. & Hill, M. J. Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks. Genome Med. 10, 14 (2018). Article PubMed PubMed Central CAS Google Scholar Gamazon, E. R. et al. Using an atlas of gene regulation ...
This chapter is initiated with the record and discussion of the diverse uses of healing clay, both for internal applications involving geophagy and edible clay and for external or topical applications involving the practices called mud therapy and peloth
Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Gen
Matthew, Yulia Newton, Cameron M. Soulette & Joshua M. Stuart UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA Angela N. Brooks, Brian Craft, Mary J. Goldman, David Haussler, Joshua M. Stuart & Jingchun Zhu Division of Applied Bioinformatics, ...
Matthew, Yulia Newton, Cameron M. Soulette & Joshua M. Stuart UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA Angela N. Brooks, Brian Craft, Mary J. Goldman, David Haussler, Joshua M. Stuart & Jingchun Zhu Division of Applied Bioinformatics, ...
Matthew, Yulia Newton, Cameron M. Soulette & Joshua M. Stuart UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA Angela N. Brooks, Brian Craft, Mary J. Goldman, David Haussler, Joshua M. Stuart & Jingchun Zhu Division of Applied Bioinformatics, ...
A human cervical cancer cell line CaSki (IFO50007)54 was obtained from the Japanese Collection of Research Bioresources (JCRB, Osaka, Japan), and grown in RPMI 1640 Medium (Nissui) supplemented with 10% FBS (Sigma-Aldrich) and 2 mM l-glutamine (Gibco) under conditions of 5% CO2 ...