protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision. Serum RBP4 levels are elevated in insuli...
Retinol-binding protein-4 (RBP4) is elevated in serum and adipose tissue (AT) in obesity-induced insulin resistance and correlates inversely with insulin-stimulated glucose disposal. But its role in insulin-mediated suppression of lipolysis, free fatty acids (FFA), and endogenous glucose production ...
RBP4 (retinol-binding protein 4) is a carrier protein that transports vitamin A (retinol) from the liver to the peripheral tissues. Synthesized primarily by hepatocytes and adipocytes as a 21 kDa non-glycosylated protein, RBP4 is secreted into the circulation as a retinol-RBP4 complex. In plasma...
The RBP4 ELISA kit is to be used to detect and quantify protein levels of endogenous RBP4. The assay recognizes human RBP4. An antibody specific for RBP4 has been pre-coated onto the microwells. The RBP4 protein in samples is captured by the coated antibody after incubation. Following ...
Serum levels of retinol-binding protein 4 (RBP4), a protein secreted by adipocytes, ar... TE Graham,Q Yang,M Blüher,... - 新英格兰医药杂志 被引量: 3249发表: 2006年 Plasma Retinol-Binding Protein-4 Concentrations Are Elevated in Human Subjects With Impaired Glucose Tolerance and Type 2 ...
该RBP4 (人源)重组蛋白 产品为重组表达蛋白,可广泛应用于包括SDS-PAGE或者其它功能研究,具体请查看产品说明书。 产品形式 保存建议 请在接收到RBP4 (人源)重组蛋白 产品后按照产品操作说明书进行保存。我们建议分装以避免反复冻融。 其他 作为中外知名的单克隆抗体和蛋白生产商,Abnova的金牌品质使其成为全球最主要抗...
Retinol binding protein 4 (RBP4), originally known as a specific transport of retinol in blood, is also a novel inflammatory and insulin resistance marker. Serum RBP4 levels are elevated in insulin resistant mice and humans with obesity and type 2 diabetes. Animal ...
BackgroundBoth increased and decreased levels of the adipokine retinol-binding protein 4 (RBP4) have been reported in cardiovascular disease, and levels of RBP4 have been related to diabetes, metabolic syndrome and cardiovascular risk. Recently, clear in vitro and ex vivo vasodilatory and inhibitory ...
作者: Protein 摘要: DESCRIPTION Species Reactivity Human/Mouse SpecificityDetects mouse RBP4/RetinolBinding Protein 4 in direct ELISA and Western Blot. In Western blots, 100% crossreactivity with recombinanthuman RBP4 is observed. Source PurificationMonoclonal Rat IgG2A Clone # 423619Protein A or G...
Elevated levels of retinol-binding protein 4 (RBP4) are observed in cardiovascular disease conditions, which prompts it as a potential drug target. Therefore, computational approach methods were implemented herein to design a novel inhibitor for RBP4. Crystal structure (2wq9) of RBP4 was retrieved ...