Human-Rag‘n’Bone Man Maybe I‘m foolish maybe I’m blind 或许是我太傻 或许是我被蒙蔽双眼 Thinking I can see through this and see what‘s behind 还以为我看穿所有 明白那背后的真相 Got no way to prove it so maybe I’m blind 无法证明什么 或许是我被蒙蔽双眼 But I‘m only human after...
Pre-clinical studies basing on immunocompromised xenograft models have previously described metastatic spread involving multiple bones, yet they have been limited to human MM cell lines [40,41,43,44,74-76]. In this study, we show that our model supports the metastatic growth of primary human MM...
HCI-031 was derived from the pleural fluid of an individual that developed metastases in fallopian tubes, bones, pleura, liver and brain. In both cases, the metastatic sublines retained the same genomic driver mutations and have similar gene expression profiles to their parental PDX lines (Fig....
When discussing their situation and their fear of changes to come, comments such as, You will just come across our bones on the land” are commonplace among village elders at the lake. Ironically, these types of comments by the Turkana are also common among their northern neighbors, the Dasan...
Tooth agenesis and orofacial clefts represent the most common developmental anomalies and their co-occurrence is often reported in patients as well in animal models. The aim of the present systematic review is to thoroughly investigate the current literature (PubMed, EMBASE) to identify the genes an...
Bone marrow cells were collected from upper and lower leg bones of inbred mice and these were suspended in RPMI1640 (Gibco) containing 2~o fetal calf serum and were sieved through Teflon mesh. The collected cells were washed and precipitated by centrifugation at 1,000 rpm for t0 min, and ...
though his large hands and big bones suggested that he would be a tall man, he was clumsily made; but his eyes were charming, and when he laughed (he was constantly laughing) his face wrinkled all round them in a jolly way. He was neither clever nor stupid, but good enough at his ...
For xenografts sample analysis, hematopoietic tissues (spleen, bone marrow (BM), and peripheral blood (PB)) were harvested from mice at sacrifice time and kept throughout the processing time on ice. BM cells were flushed from the hind leg bones and strained through a 70-μm mesh cell strain...
These results indicate that LAPC-4 xenograft cells can proliferate in murine bones, suggesting that the crosstalk between bone stroma and prostate cancer cells can occur across species. EXAMPLE 7 Isolation of Prostate Cancer Cells from Bone Marrow of SCID Mice Bearing Subcutaneous Xenografts The ...
Adjusting to an upright position was quite a challenge, especially when the bones had to support an extra-large skull.” 可知,直立行走也有缺点。我们祖先进化了上百万年,骨骼也只能支撑四肢行走和有一个相对较小的头。直立行走对人类的骨架是一个相当大的挑战,尤其是当骨骼必须支撑一个超大的头骨时。可知...