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To test this hypothesis, we analyzed chromatin accessibility data derived from bone marrow, blood, and an air pouch model of acute inflammation. These data were generated using Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq), a method that tests genome-wide chromatin accessibili...
Interpretable Machine Learning With Python: Learn to Build Interpretable High-Performance Models With Hands-On Real-World Examples Responsible AI (Hall, P., Chowdhury, R., 2023) Governance Safety Drift Marcus, G. F. (2024). Taming Silicon Valley: How We Can Ensure That AI Works for Us. MIT...
Decision-makers objectively commit to a definitive choice, yet at the subjective level, human decisions appear to be associated with a degree of uncertainty. Whether decisions are definitive (i.e., concluding in all-or-none choices), or whether the under
However, there are only a few times where there is a real assessment of whether the user-centric requirements have been attained; indeed, the performance analyses often focuses on technical indicators far from the user perceived experience, such as system memory occupancy and percentage of satisfied...
The recent turn in the debate on AI regulation from ethics to law, the wide application of AI and the new challenges it poses in a variety of fields of human activities are urging legislators to find a paradigm of reference to assess the impacts of AI an
The obvious solution is to use non-parametric tests (like the Wilcoxon test for comparing two groups, or Mann-Whitney for more than two groups). However, non-parametric tests lose power compared to the parametric tests when the assumptions hold. Thus we ran non-parametric tests in addition, ...
Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant pathways, cell cycle, neuronal protection, a
Median diagonal and off-diagonal values in matrices of Pearson’s R between two datasets were calculated in 100 region label permutations to test the non-random level of correlation between the two datasets. The resulting distributions were compared using paired Wilcoxon test. For each cell type, ...
Quantitative real-time PCR was performed using Power SYBR Green PCR master mix (Applied Biosystems, 4368706; primers are listed in Supplementary Table 11) on a 7500 Fast real-time PCR instrument (Applied Biosystems). The mRNA expression levels of genes of interest were quantified relative to ...