Using a previously published patient bulk RNA-sequencing (RNA-seq) dataset23, we carried out differential gene expression analysis between allMLL-AF4infant-ALL (n = 19) andMLL-AF4childhood-ALL (n = 5) samples. We identified 617 significantly differentially expressed genes (false discove...
It is not fixed to a single localized organ in the body, but rather is made up of numerous specialized cell types that must adaptably organize their intercellular connections to respond to pathogens and other threats wherever they may appear. We provide a systematic and quantitative view of the...
Comparison of bladder isolates with vaginal and gut isolates.AVenn diagram showing the number of bacterial species isolated from asymptomatic individuals shared among three different niches: bladder (blue;n = 68), vagina (red;n = 74), and gut (yellow;n = 175). Reference genomes ...
Epithelial regeneration is essential for barrier maintenance and organ function [36, 37]. Therefore, specific markers of intestinal stem cells (ISCs) were investigated. As depicted in Fig. 11E, CRS led to significantly decreased mRNA expression of ISCs, while Ri. intervention resulted in a pronounc...
Human activity recognition (HAR) has multifaceted applications due to its worldly usage of acquisition devices such as smartphones, video cameras, and its
organizationThe diagram shows five levels of organization in a multicellular organism. The most basic unit is the cell; groups of similar cells form tissues; groups of different tissues make up organs; groups of organs form organ systems; cells, tissues, organs, and organ systems combine to form...
What is the human reproductive system? What are the main parts of the male reproductive system? What are the main parts of the female reproductive system? human reproductive system,organsystem by whichhumansreproduceand bear liveoffspring. Provided allorgansare present, normally constructed, and funct...
They are used to monitor vitals and assist in the body’s healing process by providing organ functionality while the organs heal. Therefore, incorporating auxiliary medical equipment in the emulation is quintessential. Figure 3 shows the taxonomy of the review paper where the simulators are ...
Organ-on-a-chip (OOC) provides microphysiological conditions on a microfluidic chip, which makes up for the shortcomings of traditional in vitro cellular culture models and animal models. It has broad application prospects in drug development and screeni
(A) This diagram shows the conversion of LacCer to the ganglioside GM3 by ST3GAL5 (and then to GD3 upon α-2,8-sialylation and to 9-O-AcGD3 upon O-acetylation); both GM3 and GD3 are converted back to LacCer by NEU3. (B) Western blots of ERK1/2 and pERK1/2 from control ...