Human visual perception carves a scene at its physical joints, decomposing the world into objects, which are selectively attended, tracked and predicted as we engage our surroundings. Object representations emancipate perception from the sensory input, e
or a small number of cells, is not seen in some cancers, raising questions about whether tumors are undergoing a genetic bottleneck9,13. The presence of ecDNA amplification may explain some of these paradoxical features. Extrachromosomal oncogene amplification on circular particles that lack centromere...
The concept that the environment in which we live can have detrimental effects on our health has existed for centuries. Obvious examples of substances that
Viruses are obligate intracellular pathogens that cause infection in susceptible host cells. Virus infections could be lytic, chronic, latent or immortalizing. Viruses causing latent infection are associated with high morbidity and mortality worldwide. T
Such features are ideal to target the negatively charged surface of bacteria [1–6]. AMPs also protect humans from microbial infection. They have been identified in a variety of exposed tissues or surfaces such as skin, eyes, ears, mouth, airways, lung, intestines, and the urinary tract. ...
Introduction In the contemporary world, the mass customization of products is a competitive ad- vantage in the manufacturing domain, yet it is not easily achieved [1]. I4.0 methodologies address this challenge through novel technological concepts such as smart factories, the merging of physical ...
We characterize experiential systems by the following properties: (1) they are direct, in that they do not use complex metaphors or commands either for presentation of the information or for mediating interactions with it, (2) they support the same query and presentation spaces so as to provide...
We have performed a functional and topological analysis of housekeeping and tissue-specific networks to identify universally necessary biological processes, and those unique to or characteristic of particular tissues. Results We measured whole genome expression in 31 human tissues, identifying 2374 ...
WPMY-1 cells are incubated with SV or vehicle, and DU145 cell migration toward the stromal cells is monitored, as in D (P = 0.021). F: Protein extracts from SV (lane 1), cells (lane 2), and cells + SV (lane 3) are blotted with the indicated antibodies. Lane 1, protein ...
pathways.In this schematic1,2,3and4represent 4 individual pathways as they are traditionally considered, however a pathway exists in metabolism that can connect these 4 pathwaysviathe intermediates of each. This pathway (highlighted in black) could biochemically be more important than1,2,3or4. ...