This instability may present the opportunity for aberrant skin development if the normal establishment of commensal microbiota goes awry. Despite limited sebum production in infants (Agache et al., 1980), Propi
It must be noted, however, that it is ques- tionable whether the microbiota alterations are really cause or consequence of a specific disease; however, it has been proven a direct relationship between alterations in microbiota composition and diversity and high risk to develop specific diseases as...
2020). In terms of fundamental element cycles and some climatic parameters, human-driven changes are pushing the Earth System well outside of its normal operating range in the Holocene. In addition, the structures of the terrestrial and marine biospheres (including both abiotic (e.g. landform)...
progenitor cells, and terminally differentiated cell types. By modifying the combination of growth factors and cell isolation procedures, researchers can rapidly alter the 3D culture system to generate multiple kinds of human normal and cancerous ...
It must be noted, however, that it is questionable whether the microbiota alterations are really cause or consequence of a specific disease; however, it has been proven a direct relationship between alterations in microbiota composition and diversity and high risk to develop specific diseases as ...
(CIN) and cervical cancer. Although the virus is highly prevalent, only a small number of women have a persistent HPV infection and subsequently develop clinically significant disease. There is emerging evidence which leads us to conclude that increased diversity of vaginal microbiota combined with ...
Microbiota infection The human CNS infects the gut microbiota. In this scenario, the BBB is regarded as the primary entry site of intestinal pathogens and their metabolites [149, 150]. However, the influence of infection and entry routes through the BBB remains unclear. For this reason, a hum...
Therefore, we hypothesised that treatment of colitis with MSCs could restore the microbiota composition and function in the TNBS-induced colitis model and reduce inflammation to a normal state. Then, we inves- tigated the effects of MSC treatment on host disease sta- tus, gut microbiome ...
Much has been learned about the diversity and distribution of human-associated microbial communities, but we still know little about the biology of the microbiome, how it interacts with the host, and how the host responds to its resident microbiota. The Integrative Human Microbiome Project (iHMP,...
Innate lymphoid cells (ILCs) are largely tissue-resident, mostly described within the mucosal tissues. However, their presence and functions in the human draining lymph nodes (LNs) are unknown. Our study unravels the tissue-specific transcriptional profi