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et al. Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis. Antimicrob. Agents Chemother. 54, 4379–4388, doi: 10.1128/ aac.00498-10 (2010). 33. Magez, S., Radwanska, M., ...
cardiovascular diseases [25], and the Glutamic Acid Decarboxylase (GAD), able to catalyze the synthesis of γ-aminobutyric acid (GABA), the most common inhibitory neurotransmitter in the central nervous system that also regulates cardiovascular functions such as blood pressure and heart rate [26]. ...
A small percentage of CM infections produce progressive tissue destruction, either as a chronic fibrocavitary pneumonia or with hematogenously dissemi- nated infection beyond the chest to involve the central nervous system, skin, or skeleton. These complications disproportionately impact the ...