the human gut microbiome (previously termed the gut flora) has been the subject of study for decades; however, the high diversity of organisms in the gut and the infeasibility of standard culture techniques in identifying those organisms historically have limited their study. only within the past ...
A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464, 59–65 (2010). Article CAS Google Scholar The Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 486, 207–214 (2012). Borenstein, E., Kupiec, M....
The human microbiome has lately emerged as an important factor in health and disease. The general patterns that emerge from metagenomics studies of the microbial diversity in the human gut of healthy adults, children and infants, are that (a) the microbiome is less diverse early in life, and ...
The extreme diversity of the human immune system, forged and maintained throughout evolutionary history, provides a potent defense against opportunistic pathogens. At the same time, this immune variation is the substrate upon which a plethora of immune-a
A high-quality genome compendium of the human gut microbiome of Inner Mongolians Article 05 January 2023 Unveiling microbial diversity: harnessing long-read sequencing technology Article 30 April 2024 A unified catalog of 204,938 reference genomes from the human gut microbiome Article Open acce...
Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance Objective: In the present study, we examined the effect of a very low-calorie diet(VLCD)-based obesity program on human gut microbiome diversity and ...
Gut microbial communities represent one source of human genetic and metabolic diversity. To examine how gut microbiomes differ among human populations, here we characterize bacterial species in fecal samples from 531 individuals, plus the gene content of 110 of them. The cohort encompassed healthy chi...
Fig. 2: Human gut MAGs expand the genomic diversity of the gut microbiome. a, Reference genomes were clustered with MAGs at 95% average nucleotide identity (ANI). IMG, Integrated Microbial Genomes; PATRIC, Pathosystems Resource Integration Center. b, All OTUs were further clustered into groups ...
et al. Structure, function and diversity of the healthy human microbiome. Nature 486, 207–214 (2012). Article CAS Google Scholar Durack, J. & Lynch, S. V. The gut microbiome: relationships with disease and opportunities for therapy. J. Exp. Med. 216, 20–40 (2018). Article PubMed...
Prior studies have reported the association of microbial dysbiosis with senescence and chronic disease35. Firstly, we analyzed the diversity of the fecal microbiome among the groups and found that the diversity of the oCRC group was lower, while the fecal microbiota of patients with yCRC exhibited...