GDF-15(Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH,...
Human GDF-15 ELISA Kit from Proteintech (96 tests) . Quantitate Human GDF-15 in Serum, Plasma, Cell culture supernatant, Urine. Cat.No. KE00108.
GDF15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; MIC-1NSAID-activated gene 1 protein; MIC1Prostate differentiation factor; NAG-1; NAG-1NSAID-regulated gene 1 protein; NSAID (nonsteroidal inflammatory drug)-activated protein...
GDF15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; MIC-1NSAID-activated gene 1 protein; MIC1Prostate differentiation factor; NAG-1; NAG-1NSAID-regulated gene 1 protein; NSAID (nonsteroidal inflammatory drug)-activated protein...
Product Summary for Human GDF-15 Antibody Immunogen Chinese hamster ovary cell line CHO-derived recombinant human GDF-15Ala197-Ile308Accession # Q99988 Specificity Detects human GDF-15 in direct ELISAs. Clonality Monoclonal Host Mouse Isotype IgG2B Scientific Data Images for Human ...
(3), and would appear to function as an anti-apoptotic molecule during neuronal stress. GFRAL is a functional receptor for GDF-15, facilitating weight-loss functions of the protein through c-Ret downstream signaling (2-4). GFRAL and GDF-15 signaling is implicated in diet-based obesity and ...
Mechanistically, artesunate induces the expression of GDF15 in multiple organs, especially the liver, in mice through a C/EBP homologous protein (CHOP)-directed integrated stress response. Inhibition of GDF15/GFRAL signalling by genetic ablation of GFRAL or tissue-specific knockdown of GDF15 ...
et al. Network analyses reveal negative link between changes in adipose tissue GDF15 and BMI during dietary-induced weight loss. J. Clin. Endocrinol. Metab. 107, e130–e142 (2022). Article PubMed Google Scholar Armenise, C. et al. Transcriptome profiling from adipose tissue during a low-...
Consistent with the cytokine array results, the concentration of GDF-15 and MIF in iPSC-MSCs-CdM and BM-MSCs-CdM was measured by Enzyme-linked Immunosorbent Assay (ELISA) assay. As shown in Fig. 5c, the concentration of GDF-15 (Fig. 5c-i, 4113 ± 121 pg/mg protein vs. 559...
Detailed methods for GDF15 ELISA, preparation of samples for LC-MS/MS analysis of trophoblast organoid supernatants and reverse transcription and real-time quantitative RT-PCR (qRT-PCR) Reporting Summary Supplementary Table 1 Derivation of human trophoblast organoids. a, Reagents tested for derivation...