doi:10.1038/SJ.LEU.2404874N Prade-HoudellierE FrébetC DemurE-F GautierF DelhommeauA-L Bennaceur-GriscelliC GaudinV MartinelG LaurentV Mansat-De MasLeukemiahuman erythroid progenitor cells. Blood (2011) 117(9):2567-76. doi: 10.1182/blood-...
Proliferation of human erythroid progenitor cells is stimulated by protein kinase cα and inhibited by thrombinWe have used erythropoietin(Epo)- and stem cell factor(SCF)-dependent cultures of early erythroid progenitors in serum-free medium to study the effect of PKC- and of G protein-coupled ...
The cells appeared immature. SAR-mediated induction of γ-globin also inhibited K562 cell growth by causing arrest in G1/S, apoptosis, and delay of maturation, cellular changes consistent with the previously known effects of HU on erythroid cells. SAR also enhanced both γ- and β-globin ...
价格:¥99865 货号:Human CD36+ Erythroid Progenitor Cell Line (CD36E) 产地:北京 点击询问我要采购 竭诚为您服务! BioVector NTCC典型培养物保藏中心 联系人:Dr.Xu, Biovector NTCC Inc. 电话:400-800-2947 工作QQ:1843439339 (微信同号) 邮件:Biovector@163.com 手机:18901268599 地址:北京 已注册 ...
Microarray profiling of CD34+ cells demonstrated that a unique transcriptional pattern is activated in progenitors by F36VMpl dimerization. Ligand-inducible dimerization of intracellular Mpl in human myeloerythroid progenitors induces progenitor expansion and erythropoiesis through molecular mechanisms that are ...
progenitor cells (CD34/HSPCs) from healthy donors. Exogenous synthetic C2- and C6-ceramide as well as bacterial SMase inhibited erythroid differentiation in erythropoietin-induced (Epo)CD34/HSPCs shown by the analysis of various erythroid markers. The neutral SMase inhibitor GW4869 as well as the ...
All three cell types are stimulated by species nonspecific diffusible factors in irradiated mice (or inhibited by factors in nonirradiated mice). These studies suggest that an analogy exists between the organization of erythroid and neutrophilic progenitor cells....
High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. PLoS One 8, e58757 (2013). Article CAS PubMed PubMed Central Google Scholar Wang, J. et al....
描述 Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokin...
Josefsen D, Myklebust JH, Lomo J, Sioud M, Blomhoff HK & Smeland EB (2000) Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells. Stem Cells (Dayton, Ohio) 18, 261-272....