Summary: Human embryonic stem cell therapy, what is the attitude of the public?. [German]Rubin, B P
Cultured pluripotent stem cells show a dynamic spectrum of pluripotency states, reflecting stages in pre-to-post-implantation development in vivo, principally the transition from the naïve to the primed state41,42,43. This dynamic spectrum of pluripotency states exhibits distinct molecular and functio...
Charles E.Murry, ...LiorGepstein, inHeart Development and Regeneration, 2010 Publisher Summary This chapter provides a brief overview of humanembryonic stem cells, and explores their use as systems to understand basic developmental biology and physiology of the human heart. It summarizes the initial...
2 Progressive development of posteriorized embryonic-like sac. a, Protocol for generating P-ELS. After initial seeding and clustering of human ES cells (t = −18 to 0 h), lumenogenesis leads to the formation of the epiblast-like cyst containing a single central lumen. BMP4 stimulation (...
It is not known why the coronary arteries almost always originate only from the right and left aortic sinuses of Valsalva, since the structure and conditions appear to be the same for all six sinuses of the embryonic great arteries. We sought a possible mechanical explanation for the phenomenon...
Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based therapies that are capable of restoring lost cell and tissue function. These unique cells are able to self-renew indefinitely and have the capacity to differentiate in
The development and use of human embryonic stem cells (hESCs) in regenerative medicine have been revolutionary, offering significant advancements in treating various diseases. These pluripotent cells, derived from early human embryos, are central to modern biomedical research. However, their application is...
In summary, our data provided the first and earliest cellular atlas of the human embryonic TMJC. The present results show that chondrocytes from secondary cartilage differentiate in 4-month-old TMJC and that chondrocytes differentiate later than other cell clusters. Our results also demonstrated the...
human totipotent-like stem cells with expanded embryonic/extra-embryonic potency. In addition, these goals will benefit from novel BC strategies (Fig.3) that facilitate human tissue development within engineered lineage-restricted animal embryo hosts with human-compatible gestational time-frames (Fig.4)...
We describe the conspicuous morphological features of the developing human heart as they appear in consecutive stages of development. The descriptions of the components of the embryonic hearts follow the bloodstream, proceeding from the venous to the arterial pole. The developmental processes in human ...