A comparison of human DNA with that of 12 other animals.(USA)(Brief Article)Amodeo, Christian
The increased complexity in post-transcriptional processing and restriction of expression of the human genes primarily to central nervous system tissue as compared with pig and mouse suggests that PCDHX/Y is potentially a good candidate to account for human-specific features of the CNS. 展开 ...
Expression of most of the 179 core inflammation genes increased in inflamed neutrophils (Fig.4a). A gene set was created based on the 179 core inflammation genes, and changes in expression were tested compared to random background genes with the same expression abundance. A significant increase i...
compared to humans, cattle has a different population structure, such as smaller effective population size (Ne ~100), higher linkage disequilibrium (LD) among genomic variants, and higher
3.should(not)havedone句型[教材原句]Somescientistssaytheteamshouldnothaveannouncedtheirfindingssoearly—theyshouldhavelookedmorecarefullyfortheDNAfromCopernicus’motherorherrelativestochecktheresults,asitisthemother’sDNAthatispassedonintacttoherchild.一些科学家认为,研究小组不应该这么早公布研究结果,因为正是他母...
DNA topoisomerase II (TOP2) is an enzyme that resolves DNA topological problems and plays critical roles in various nuclear processes. Recently, a heterozygous H58Y substitution in the ATPase domain of human TOP2B was identified from patients with autism
Interestingly, the expression levels of both murine insulin genes were substantially lower in the PMP-derived cells as compared to the islet-derived cells. The low insulin mRNA expression revealed by qPCR could be validated at the protein level by the MIP-GFP transgene product's fluorescence ...
35 human depression datasets, including those used to create the portraits of depression, were compared with each of the animal models (Supplementary Table 2). Brain region information is provided for humans and animals so direct region to region comparisons can be made. As expected, the top con...
Lastly, module F may have been associated with technical variables, with more commitment seen in cells when compared with nuclei (Extended Data Fig. 3). Aging shifts epicardial focus from angiogenesis to immune response We then examined the function of each gene module using GprofileR in an ...
Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME), a computational pipeline that identifies a unique class of long noncoding RNAs (l