The binary STARR-seq design allows looking for relatively short-range interactions between promoters and enhancers, and the details of machine learning analysis used for testing such interactions are detailed in the Supplementary Methods. TSS prediction All the promoter models were trained on data where...
A condition whereby two different genomes are found in a single individual, typically resulting from a post-fertilization mutation that is found only in the daughter cells of a subset of embryonic cells and thereby results in different phenotypic expression in different tissues. A frequent type of ...
Free access to Primer Design Program QuikChange Lightning Live Webinar: Accelerate your research without sacrificing mutation efficiency, reliability and accuracy. Click here to view New!Multiply the power of QuikChange to easily do scanning and combinatorial mutagenesis with QuikChange HT ...
3.1. PSEN1 ΔE9 Mutation in Human Glial Progenitors Improves Spatial Learning and Memory at 16 Months after the Transplantation To evaluate the effect of the PSEN1ΔE9 mutation in transplanted human glial progenitor cells on mouse locomotion, emotional state, and cognitive function, we designed a ...
Design of an effective piezoelectric microcantilever biosensor for rap-id detection of COVID-19. J. Med. Eng. Technol. 2021, 14, 1. [Google Scholar] Zhang, K.; Zhang, L.; Fu, L.; Li, S.; Chen, H.; Cheng, Z.-Y. Magnetostrictive resonators as sensors and actuators. Sens. ...
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1a. The design of the two donor constructs was to allow the neomycin or EGFP to be expressed along with, but separately from, MLC-2v expression after insertion into the 3' terminal of the MYL2 gene. The purpose of this design was to avoid formation of fusion proteins which may severely...
suitable for use as a hybridization probe, which can be used, e.g., to a identify nucleic acid molecule encoding a polypeptide of the invention, DGAT2 family member mRNA, and fragments suitable for use as primers, e.g., PCR primers for the amplification or mutation of nucleic acid ...
Design In vitro study with human endometrial tissues and cultured human endometrial cells. Setting University hospital. Patient(s) Thirty-seven women undergoing hysterectomy for benign disease. Intervention(s) Human endometrial tissues were collected for in situ hybridization. Culture medium of human endom...