To test this hypothesis, we analyzed chromatin accessibility data derived from bone marrow, blood, and an air pouch model of acute inflammation. These data were generated using Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq), a method that tests genome-wide chromatin accessibili...
Early erythroid precursors were studied in human bone marrow smears to provide more information on small proerythroblasts – "microproerythroblasts" – using a silver reaction to demonstrate silver stained nucleolar organizer regions (AgNORs) and light microscopic densitometry of large irregularly shaped...
Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma, cartilage, fat, and bone. Although a significant progress has been made toward recognizing about the phenotypic characteristics of MSCs, the true identity and properties of MSCs ...
knowledge of the human Y chromosome, its genes and how the defects in these genes lead to male infertility. The human Y chromosome Mammalian sex chromosomes evolved from autosomes at least 180 million years ago. The first step in differentiation of the Y chromosome involved the acquisition of th...
Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and ...
Human herpesvirus 6 DNA in cerebrospinal fluid specimens from allogeneic bone marrow transplant patients: does it have clinical significance? Clin Infect Dis 1999;28562- 568PubMedGoogle ScholarCrossref 13. Sgarabotto DBuoro SMengoli C et al. PCR in meningoencephalitis diagnosis. Scand J Infect...
Periodontal ligament-Associated protein-1 delays rat periodontal bone defect repair by regulating osteogenic differentiation of bone marrow stromal cells and osteoclast activation 2018, International Journal of Molecular Medicine Cell survival and gene expression under compressive stress in a three-dimensional ...
Mobilized peripheral blood is increasingly used instead of bone marrow as a source of autologous hematopoietic stem/progenitor cells for ex vivo gene therapy. Here, we present an unplanned exploratory analysis evaluating the hematopoietic reconstitution
This result was consistent with the previous studies of human bone marrow- and adipose tissue-derived MSCs, which showed that spheroid-culture caused a significant upregulation of angiogenetic genes, and enhanced expression of pro-inflammatory and anti-inflammatory genes by the gene microarray analysis...
The early B lymphopoiesis in mammals is regulated through close interactions with stromal cells and components of the intracellular matrix in the bone marrow (BM) microenvironment. Although B lymphopoiesis has been studied for decades, the factors that are implicated in this process, both autocrine an...