Organisms can contribute to ecosystem structure and processes in a variety of ways, and thus biological diversity is important for sustained ecosystem function andintegrity. Various species of microbes, plants, and animals in aquatic systems govern vital ecosystem processes such as decomposition and nitro...
The 25000 most accessible windows were subjected to singular value decomposition (SVD), and the RunHarmony function was used to remove batch effects with 2-30 LSI components. The 2-30 Harmony components were then used for UMAP (n.neighbors = 50 L, min.dist = 0.5) and Louvain ...
074 cells from fetuses with Ts21 and 164,478 cells from fetuses with disomy (Supplementary Tables1and2). We examined putativeGATA1somatic mutations from the scRNA-seq data; however, none was likely to impact GATA1 function (Supplementary Note1). We identified eight major blood ...
However, their large-scale use and their decomposition rates in the environment cause these compounds to accumulate in soils, from where they subsequently enter groundwater and rivers [101]. A recent study detected the organothiophosphate insecticide chlorpyrifos in air and seawater in the Arctic, ...
A dominant trend has focused on the decomposition and robotization of core construction tasks such as painting, bricklaying, and surveying (Warszawski 1984; Ueno et al. 1986; Skibniewski and Russell 1989; Ochoa-Franco et al. 1994; Warszawski and Navon 1998; Son et al. 2010; Saidi et al....
Multivariate linear regression models were then constructed for each of the 241 genera and based on the adjusted p value (p < 0.05, BH) of these models, we selected 199 genera for the downstream variation decomposition analyses. To evaluate the contributions of each variable, we used a ...
The NMF model was trained for a range of factors and tissue zones R = {8,…,35} and the decomposition into 17 factors was selected as a balance between segmenting relevant tissue zones (lymphoid structures, blood vessel types) and over-separating known zones into several distinct factors. ...
A. et al. Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776–779 (2014). Article CAS PubMed PubMed Central Google Scholar Van Dongen, S. Graph clustering via a discrete uncoupling process. SIAM J. Matrix Anal. Appl. 30, ...
(Methods). HSCs demonstrated multipotent lineage commitment; however, Ts21 HSCs showed much greater bias towards the erythroid and megakaryocytic lineages than disomic HSCs (Fig.3b), with greaterGATA1(which encodes a transcription factor essential for erythroid lineage development) gene body and ...
The antibodies of the invention are useful in the prophylaxis of HIV and in the diagnosis, and treatment of humans suffering from HIV infections. These human monoclonal antibodies are directed against HIV protein gp41 and protein p24 (and the precursors and decomposition products of such proteins)...