Alphaherpesviruses have a broad host range; they replicate rapidly in many types of cells. Although these are highly lytic viruses, members of this subclass can establish latency in neurons and glial cells. This group includes human HSV-1 and HSV-2, humanVZV, andbovine herpesvirustype 1 (BHV...
Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. J Virol. 2009;83:10677–83. 11. Thompson RL, Sawtell NM. The herpes simplex virus type 1 latency associated transcript is required for the maintenace of reactivation competent latent infection. J ...
Human alphaherpesviruses (αHHV)—herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV)—infect mucosal epithelial cells, establish a lifelong latent infection of sensory neurons, and reactivate intermittingly to cause recrudescent disease. Although chronic αHHV infections ...
Human cytomegalovirus (hCMV) is a highly prevalent pathogen that, upon primary infection, establishes life-long persistence in all infected individuals. Acute hCMV infections cause a variety of diseases in humans with developmental or acquired immune def
Marek's disease virus (MDV) is an alphaherpesvirus for which infection is strictly cell associated in permissive cell culture systems. In contrast to most ... C Denesvre,C Blondeau,M Lemesle,... - 《Journal of Virology》 被引量: 52发表: 2007年 β-Naphthoflavone Caused Up-Regulation of ...
Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV; human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong infections in ganglia. Following primary infection and establishm... J Rovnak,PGE Kennedy,H Badani,... - 《Journal of Ge...
Recently, it was reported that the forkhead box O (FoxO) transcription factor promotes human cytomegalovirus (HCMV) replication via direct binding to the p
(1994). Inhibition of feline immunodeficiency virus gene expression and replication by alphaherpesvirus ICP4 homologues. Journal of General Virology, Vol. 75, No.10., (October 1994), 2783-2787. ISSN 0022-1317 Kawaguchi, Y., Maeda, K., Pecoraro, M.R., Inoshima, Y., Jang, H.K., Koh...
For example, an “aG” suffix would indicate that proteins of this group are found in some (but not all) members of human alphaherpesvirus species (lowercase “a”), and members of both human gammaherpesvirus species (uppercase “G”). Families which have a (some) domain(s) in common ...
Like the HSVs, VZV is an alphaherpesvirus. The typical route of infection for VZV is the mucosa of the upper respiratory tract. After primary replication in the mucosal epithelium, the virus enters the circulation and eventually localizes to the skin, where it causes two distinct syndromes. ...