Bockaert J, Fagni L and Dumuis A (1997) 5-HT4 Receptors: an Update., in Serotoninergic Neurons and 5-HT Receptors in the CNS (Baumgarten HG and Gothert M eds) pp 439-465, Springer-Verlag, Berlin.Bockaert J, Fagni L, Dumuis A (1997) 5-HT 4 receptors: an update. In: ...
Eglen RM (1997) 5-Hydroxytryptamine (5HT4) receptors and central nervous system function: An update. In: Jucker E (ed.): Progress in Drug Reseach 49: 9–21Eglen RM (1967) 5-Hydroxytryptamine (5-HT) 4 receptors and central nervous system function: an update. Prog Drug Res 49:9–24...
The invention relates to the use of a 5-HT4 receptor antagonist in the manufacture of a medicament for the prophylaxis or treatment of atrial remodelling in a mammal. Preferably, the antagonist is N-[(1.nbutyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxa...
Antagonism by SB 204070 of 5-HT-evoked contractions in the dog stomach: an in-vivo model of 5-HT4 receptor function.R Chatterjee, M J Benzinger, J L Ritter, D L Bissett Index: J. Pharm. Pharmacol. 47(3) , 219-22, (1995) Full...
In in vivo functional assays, 17m dose dependently inhibited the Bezold-Jarisch reflex and induced 5-HT(1A)-mediated behaviors, and in an IBS animal model, 17m significantly inhibited stress-induced defecation. Pretreatment by WAY-100635 (5-HT(1A) antagonist) significantly attenuated but did not...
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea...
Diterpene Total Synthesis : An Improved Stereoselective Route To (±)-3,4,5,5A, 7,8,8a±,8b-Octahydro-2a±,5a-Dimethyl-2H-Naphto-|1,8-Bc|Furan-2,6-(2Ah)-DioneThe synthesis of the title compound 13, via a photochemical (2 + 2) annellation procedure and a highly stereo-selective ...
Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipationdoi:10.1111/apt.12571BackgroundHighly selective 5-HT4 agonists have been suggested for the treatment of chronic constipation (CC). AimTo assess the effects of ...
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根据题干前面的"has had a profound impact(有一个深远的影响)"和空格后面的"Chinese society(中国社会)"可知,此处要表达的意思是"中国书籍文化的发展对中国社会有一个深远的影响",又因"对….有影响"用到的短语是"have an impact on",故填on/upon。(9)考查冠词。句意:从古代经典到现代...