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A more recent study suggested that another natural product synthesized by Myxococcus xanthus, termed myxovirescin, inhibited Lsp based on whole-cell assay experiments (Paitan et al., 1999, Xiao et al., 2012). Unfortunately, the limited stability (Table S2), in vivo ineffectiveness, scalability,...
A significant cytotoxicity effect of this toxin was observed on Vero and Caco-2 cells, although its haemolytic activity was limited [14,15]. Hbl and Nhe are tripartite enterotoxin complexes and belong to the α-helical pore-forming toxins family (α-PFT), like the Haemolysin E (HlyE) from...
Mucin Protein Abundance Caco-2/HT29-MTX cells were seeded at 2 × 105 cells/well in six-well culture plates (Corning) and treated with mycotoxins (as described above) in serum-free media for 48 h. Cell-culture supernatants were collected and stored at −80 ◦C until required for ...
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