MicroRNA-132 attenuates LPS- induced inflammatory injury by targeting TRAF6 in neuronal cell line HT-22. J Cell Biochem. Williams, AE, Perry, MM, Moschos, SA, Larner-Svensson, HM, and Lindsay, MA (2008). Role of miRNA-146a in the regulation of the innate immune response and cancer. ...
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此外,为了确认LPS的最佳时间和剂量对黏液屏障功能的影响,在Caco-2/HT-29共培养分化15天后,使用100、200、400、800和1000 μg/mL LPS分别在12、24、36、48小时刺激Caco-2/HT-29共培养细胞。根据观察结果,后续测试选择400 μg/mL LPS刺激Caco-2/HT-29共培养细胞。实验还观察到,LPS(+)组在LPS刺激12、24、3...
Caco-2/ HT-29共培养分化15天后,在24、36、48和60小时用LPS(LPS +)或0.01M PBS (LPS-)刺激细胞。LPS(+)组和LPS(-)组MUC2 mRNA和蛋白质在24小时时的表达水平高于其他时间点。因此,Caco-2/HT-29共培养细胞在LPS刺激24小时前用Lipofectamine™2000转染siRNA MUC2构建物。这些综合结果表明,用siRNA转染和LPS...
脂多糖(LPS)是内毒素的主要有毒物质,紧密结合到其细胞壁的最外层,当细菌死亡溶解或用人工方法破坏菌细胞后才释放出来。人类胃肠道具有大量复杂的共生和有害革兰氏阴性细菌,当肠黏膜屏障完好时,它们不会损害肠腔。然而,当肠黏膜免疫屏障受损时,许多内毒素会转移到血液中,引起内毒素血症。因此,确保肠黏膜屏障的完整...
interacts with other proteins via its EVH1-like domain, which specifically binds to the proline-rich sequences of PPXXF (where X is any amino acid)17, a similar sequences of PXXF in TRPC (LP(P/X)PFN) and phosphoinositide 3 kinase enhancer L (PKPF)35,36,37, or a LPSSP sequence35...
SMW-AUTOBLOK Spannsysteme GmbH LPS-X-A-50Brinkmann Pumps TB100/350+001EM-TECHNIK 2N001P40PT D06RADIO-ENERGIE RCI90B-HS4-1024-5+9445/009RADIO-ENERGIE CWH7129//10G30H//0249K//0712DRRAFI GmbH & Co. KG 1.15.114.906/0000MTS RHM0700MP101S1B8100+电缆10米+Phoenix 2757322Turck 1056803MTS RHM...
在LPS-活化的混合胶质细胞中,Loxapine(0.2 μM,2 μM和20 μM)能够减少IL-1β和IL-2分泌。 别名 琥珀酸洛沙平, 丁二酸洛沙平, Loxapine succinate salt, Loxapac, Daxolin, Cloxazepin 化学信息 分子量 445.9 分子式 C22H24ClN3O5 CAS No. 27833-64-3 Smiles OC(=O)CCC(=O)O.CN1CCN(CC1)C1=...
Because previous studies have shown that LPS resulted in a long-lasting neuro-inflammation and persistent changes in neurophysiological, cognitive and behavioral parameters4,22–24, we administered mice with endotoxemia by an intra-peritoneal injection of LPS dissolved in saline at a dose of 10 mg...