During infection with herpes simplex virus type 1 (HSV-1), VP16 servesmultiple functions, including transcriptional activation of viral immediate early genes and downregulation of the virion host shutoff protein vhs. Furthermore, VP16 has been shown to be involved in some aspect of virus assembly...
HSV-1感染可以激活宿主细胞的抗病毒天然免疫,然而病毒同时也进化出多种策略来逃逸宿主的抗病毒免疫并建立终身潜伏感染。郑春福教授实验室的研究发现HSV-1编码的多种蛋白,如VP24、UL46、US3、VP16、UL36、UL41、VP22、UL42、ICP0、UL24、US11等可干扰宿主的抗病毒天然免疫信号通路,下调IFN-I和炎症因子的转录和表...
Ⅰ型单纯疱疹病毒(herpes simplex virus1,HSV-1)在宿主体内形成两种感染模式,不同感染模式的建立与病毒α基因的表达相关.作为病毒α基因表达产物之一的ICP22在病毒复制中发挥了多重作用,但其确切功能尚不清楚.实验利用氯霉素乙酰转移酶(chloram-phenicol acetyl transferase
OPTN deficiency leads to increased levels of the essential HSV-1 proteins, VP16, and gB. Furthermore, OPTN deficiency leads to diminished host immune responses to ocular HSV-1 infection, increased susceptibility to herpes encephalitis, and long-term loss of cognition. Results OPTN restrict spread ...
详细解释: 以下为句子列表: 英文: Analysis of biological roles of VP16 in cultured cells infected with HSV-1 by RNA interference; 中文: 三种小干扰RNA干扰VP16 mRNA对单纯疱疹病毒-1复制的影响研究更详细... 英文: MethodsSpecific antibodies and DNA to HSV-1 were measured in 51 patients with AMI(...
HeLa or A549 cells were infected with HSV-1 (MOI 1), and the MR, and viral proteins VP16 and gD, detected by western blot at 0, 6, 12, 24, 36, and 48 h post-infection. (d) Induction of MR protein by HSV-1 following MR depletion. HeLa cells were transfected with control RS...
(ab110226) Anti-HSV1 + HSV2 VP16 antibody [LP1] an Antibody by Abcam Applications: WB Reactivity: Broad (ab110227) Anti-HSV1 gH antibody [BBH1] an Antibody by Abcam Applications: WB Reactivity: Broad Journal Viruses Volume 7 Issue 3 Pages 915-38 Publication Date ...
您现在的位置:生物医药大词典 >> 通用词典 >> 词汇解释: HSV-1 Protein VP16 HSV-1 Protein VP16 分享到: HSV-1蛋白质VP16分类: 生物学 | 查看相关文献(pubmed) | 免费全文文献 详细解释:以下为句子列表:分享到: 赞助商链接 你知道它的英文吗? ·HTLV-2 ·HTLV-1 ·HTLV病毒 ·HTLV感染 ...
Mouse primary microglia were infected with recombinant (VP16-GFP) HSV-1 strain (DG-1) at a multiplicity of infection (MOI) of 10 at 37 °C for 30 min, incubated with citrate buffer (pH 3) at room temperature for 1 min to remove virus outside cells, and fixed with 4% paraformaldehyde...
a. The Vero cells infected by VP26 mutant HSV1-UG were observed under fluorescence microscope at 12, 16 and 24 h. b. Growth curve of HSV1-UG compared with that of wild type HSV-1 in Vero cells. c. Electro-microscope observation of cells infected by HSV1-UG(X30, 000). Full size ...