HSV-1 encodes its own RING-finger E3 ubiquitin (Ub) ligase, Infected Cell Protein 0 (ICP0), that directly interfaces with component proteins of the Ub pathway to inactivate host immune defences and cellular processes that restrict the progression of HSV-1 infection. Consequently, ICP0 plays a...
HSV1早早期蛋白ICP0泛素化TRAF6并协同其激活NFκB,HSV1早早期蛋白ICP0泛素化TRAF6并协同其激活NFκBκB,蛋白,泛素,泛素化,TRAF6,泛素蛋白,κB蛋白,NFκ..
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npg Regulation of HSV-1 LAT and ICP0 by thyroid hormone receptor 588 TRE is the binding site of transcription factor thyroid hormone receptors (TRs). The regulatory activity of TR is dependent on the ligand thyroid hormone. Thy- roid hormone is produced by the addition of iodine to tyrosine...
Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100. Herpes simplex virus type 1 (HSV-1) mutants that fail to express the viral immediate-early protein ICP0 have a pronounced defect in viral gene expression a... Everett,Roger,D.,... - 《Jou...
HSV-1 ICP0 (11060) (HSV-1 ICP0 (11060)) Basic informationSupplier Basic informationMore Product Name:HSV-1 ICP0 (11060) Synonyms:HSV-1 ICP0 (11060) CAS: MF: MW:0 EINECS: Mol File:Mol File Browse by Nationality Suppliers>China suppliers...
HSV-1 ICP0 (11060) 中文名: 中文别名: CBNumber: CB05636035 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商2 HSV-1 ICP0 (11060)化学性质 安全信息 HSV-1 ICP0 (11060)性质、用途与生产工艺 HSV-1 ICP0 (11060)上下游产品信息 ...
The herpes simplex virus type 1 (HSV-1) encoded E3 ubiquitin ligase, infected cell protein 0 (ICP0), is required for efficient lytic viral replication and regulates the switch between the lytic and latent states of HSV-1. As an E3 ubiquitin ligase, ICP0 directs the proteasomal degradation ...
4. Interplay between ICP0, chromatin remodelling, and intrinsic immunity 5. ICP0 modulation of the cellular DNA Damage Response (DDR) pathway 6. ICP0 scrambles innate immune pathways 7. ICP0 and HSV-1 latency 8. Future Directions: Identification of new ICP0 substrates and host responses to ...