Serum was tested for HSV-specific IgG antibodies at enrollment and at 12, 24, and 52 weeks using the University of Washington Western Blot, which differentiates between HSV-1 and HSV-2 infection.8Samples were considered HSV-1 or HSV-2 p...
Since the antibody against HSV-2 infection (IgG) provides life-long immunity [35], we fitted I+R to the observed data of the number of sero-positive cases for the estimation of c and ϕ. To estimate c and ϕ, endemic equilibria of I i and R i were solved numerically with varied...
7.1% of patients were positive for HSV2 (IgM), and there was 92.9% negative for HSV2 (IgM). 9.0% of patients were positive for HSV2 (IgG) while there were 91.0% HSV2 (IgG) negative. Conclusion: the prevalence of HSV1 is more than of HSV2 in Syrian Arab republic....
Results Among the 82 participants, the median (range) age was 26 (16-64) years, 54 (65.9%) were women, and 42 (51.2%) had primary HSV-1 infection. At 2 months, HSV-1 was detected from the genital tract in 53 participants (64.6%) and in the mouth in 24 participants (29.3%). ...
As expected, we observed a larger proportion of HSV-1-positive cells in the STING-deficient mice as compared with WT mice (Fig. 2d–g). The staining for HSV-1 antigens exhibited a preferential nuclear pattern consistent with HSV-1 replication occurring in the nucleus (Fig. 2d). However, ...
A study sponsored by GlaxoSmithKline revealed that the gD2 vaccine, admin- istered with MPL and alum as adjuvants, showed a high efficacy of 74% in HSV-1/HSV-2 seronegative women but was not efficacious in HSV-1 seropositive and HSV-2 seronegative women. It was not effective in men ...
Arrows are used to illustrate the presence of a positive (↑), negative (↓), or no (→) association between infection and infertility, respectively. Table 1. Characteristics of the included eight studies. First Author, year, and countryStudy designStudy populationExposure (CT/HSV/HPV) and ...
Patterns of expression differ slightly in the adult: NT-3-specific hybridization was limited only to inner hair cells, which are innervated by TrkC-positive, Type I SGNs (4, 14, 15). Type I SGNs are the primary auditory afferent neurons that deliver sound signal information from inner hair ...
the effect of JZ-1 on the development of HSV-2. Our research found that JZ-1 gel can effectively alleviate genital herpes in mice. Its efficacy is as good as acylovir. At the practical level, it confirmed the positive effect of JZ-1 on HSV-2 infection suggested by network pharmacology...
For mass spectrometry (MS) analysis, survey full-scan mass spectra were acquired within the range of 100–1700 m/z in positive electrospray mode, with 100 ms accumulation and ramp time for each. The single acquisition cycle (1.16 ms) consisted of one full TIMS MS scan and 10 parallel accum...