Mock-transfected (solid line) or MR-specific siRNA-transfected (dashed line) HeLa cells were infected with HSV-1-eGFP (MOI 1) and GFP-positive cells quantified by flow cytometry 24 hr post-infection. (d) The MR is anti-viral to HSV-1. HeLa cells were transfected with negative control...
Of 124 false-positive sera, 20% and 39% had an index >3.50 in the HSLT and Liaison screening assays, respectively. In both assays, 51% of 63 indeterminate sera (inhibition by HSV-1 lysate) had indices >3.50. Similarly, ≥75% of 75 true-positive samples exhibited indices >3.50 in both...
Results We evaluated test results on 442 persons, of whom 49% were women, with a median age of 36 (range 18鈥 68). Overall, by UW WB, 61 persons tested HSV-2 seropositive only, 81 tested HSV-1 and HSV-2 seropositive, 170 were HSV-1 seropositive only, and 130 were seronegative ...
Figure 5.HSV-2 infection induces caspase-1–dependent pyroptosis in GH mice. (A) Representative western blots for NLRP3, IFI16, ASC, caspase-1, cleaved caspase-1 p20, GSDMD, GSDMD-N protein expressions in the vulva, and the quantification of western blots (B-H). (I) ELISA results for ...