了HSP60/HSP10各亚基蛋白相应的突变体,并对它们产生的表型进行初步的观察分析.主要研究结果如下:(1)本研究从ABRC突变体库获得了hsp10-1,hsp10-2,hsp60-2,hsp60-3a和hsp60-3b五种纯合突变体,与野生型相比,hsp10-1纯合突变体表现生长缓慢,莲座叶数目减少,根短,晚抽薹以及在生殖方面缺陷的表型;hsp10-2,hsp...
The data show that Hsp60 and Hsp10 undergo changes in levels and distribution inside cells and tissues, including invasion of the extracellular space and plasma, with age and health status and in relation with specific pathologies. The physiological and/or pathological significance of these changes ...
The mammalian molecular chaperone, HSP60, plays an essential role in protein homeostasis through mediating protein folding and assembly. The structure and ATP-dependent function of HSP60 has been well established in recent studies. After ATP, GTP is the
The involvement of Heat Shock Proteins (HSP) in cancer development and progression is a widely debated topic. The objective of the present study was to evaluate the presence and expression of HSP60 and HSP10 in a series of large bowel carcinomas and loco
We here summarize the knowledge on the effects of disturbances of the function of the HSP60/HSP10 chaperonin complex by disease-associated mutations. 展开 关键词: HSP60 chaperonin neurological disease protein folding problem mitochondria gene variation ...
HSP10,HSP60,分别)都被映射2号染色体上, 翻译结果2复制译文编辑译文朗读译文返回顶部 翻译结果3复制译文编辑译文朗读译文返回顶部 热和热休克蛋白 60,分别) 具有 2、 染色体上的映射 翻译结果4复制译文编辑译文朗读译文返回顶部 HSP10和hsp60分别为已映射在2号染色体短臂, ...
Expression of heat shock proteins HSP10, HSP27, HSP60, HSP70, and HSP90 in urothelial carcinoma of urinary bladder. J. Cancer Mol., 2006, 2(2), 73-77.Cappello F., David S., Ardizzone N., Rappa F., Marasà L., Bucchieri F., Zummo G. (2006) Expression of heat shock proteins...
The yeast wild-type strains YPH499, YPH499 arg4Δ, and JK9–3d (the wild type for hsp10ts and hsp60ts); the wild-type strain for ssc1–42; and the mutant strains mtHsp70His, ssc1–42, hsp10ts, and hsp60ts have been described before (39, 44, 54). For SILAC-based mass spect...
These proteins include: (i) the major chaperonin Hsp60 (or P1), which was identified in mammalian cells as a protein altered in mutants resistant to microtubule inhibitors and is involved in numerous functions at the cell surface and in other compartments; (ii) the Hspl0 or Cpn10 protein,...
产品名称: HSP60重组蛋白 基因名: HSPD1 Uniprot No.: P10809 别名: 60 kDa chaperonin; 60 kDa heat shock protein; mitochondrial; CH60_HUMAN; Chaperonin 60; Chaperonin; 60-KD; CPN60; fa04a05; GROEL; heat