了HSP60/HSP10各亚基蛋白相应的突变体,并对它们产生的表型进行初步的观察分析.主要研究结果如下:(1)本研究从ABRC突变体库获得了hsp10-1,hsp10-2,hsp60-2,hsp60-3a和hsp60-3b五种纯合突变体,与野生型相比,hsp10-1纯合突变体表现生长缓慢,莲座叶数目减少,根短,晚抽薹以及在生殖方面缺陷的表型;hsp10-2,hsp...
抑制细胞外的Hsp60后,热应激后H9C2大鼠心肌细胞内编码Hsp60和Hsp10蛋白的基因表达量急剧增加,Hsp60相关蛋白Hsp10的表达也显著升高,但是Hsp60的含量则显著降低,这可能是由于细胞膜上的Hsp60与加入细胞培养基中的抗体结合后,无法再结合检测抗体,导致其水平显著下降.该研究结果也进一步说明,热应激过程中Hsp60和Hsp10既...
hsp60-3ahsp60-3b纯合突变体相对于野生型超氧阴离子的含量分别增加了6,1.1,1.1,1.3,2,2,3.5倍.(4)对hsp10-1纯合突变体进行RNA-seq分析,共得到1079个差异基因,与野生型植株相比,上调的有786个,下调的有293个,这些基因主要参与转录调控,蛋白折叠,氧化磷酸化,对外界刺激的响应(缺氧,缺水,氧化,盐,伤害)和...
The data show that Hsp60 and Hsp10 undergo changes in levels and distribution inside cells and tissues, including invasion of the extracellular space and plasma, with age and health status and in relation with specific pathologies. The physiological and/or pathological significance of these changes ...
2006. HSP60 and HSP10 Down-Regulation Predicts Bronchial Epithelial Carcinogenesis in Smokers with Chronic Obstructive Pulmonary Disease. Cancer 15: 2417-2424... F Cappello,AD Stefano,S David,... - 《Cancer》 被引量: 0发表: 2006年 Chronic inflammation, chronic obstructive pulmonary disease, and...
The effects of Hsp10 and Hsp60 on Bcl-2 family could not be explained by the abundance of Bcl-2 family mRNA levels. Hsp60 interacted with Bcl-xl and Bax in the cardiomyocytes in vivo. The effect of Hsp10 and Hsp60 on the abundance of Bcl-xl could not be blocked by cycloheximide. ...
HSP10和HSP60之间体现在结构和本地化 翻译结果2复制译文编辑译文朗读译文返回顶部 在Hsp10 和 Hsp60 之间反映在结构和本地化中 翻译结果3复制译文编辑译文朗读译文返回顶部 热与热休克蛋白 60 之间被体现在结构和本地化 翻译结果4复制译文编辑译文朗读译文返回顶部 ...
翻译结果3复制译文编辑译文朗读译文返回顶部 热和热休克蛋白 60,分别) 具有 2、 染色体上的映射翻译结果4复制译文编辑译文朗读译文返回顶部 HSP10和hsp60分别为已映射在2号染色体短臂,翻译结果5复制译文编辑译文朗读译文返回顶部相关内容 a湍急的 Rapids [translate] ...
The mammalian molecular chaperone, HSP60, plays an essential role in protein homeostasis through mediating protein folding and assembly. The structure and ATP-dependent function of HSP60 has been well established in recent studies. After ATP, GTP is the
The involvement of Heat Shock Proteins (HSP) in cancer development and progression is a widely debated topic. The objective of the present study was to evaluate the presence and expression of HSP60 and HSP10 in a series of large bowel carcinomas and loco