它们也存在于脐带血和少量的外周血中。2.1 骨髓造血干细胞(HSCs)是一种骨髓来源的多能干细胞。从骨髓中获取造血干细胞通过外科手术，从两个髂骨后嵴分次采集。骨髓中每10万个细胞中约有1个是长期造血干细胞(LT-HSC)。2.2 外周血大部分造血干细胞来源于骨髓，少量的干细胞和祖细胞在血液中循环。人类造血干细胞...
The stem cell theory that all blood cells are derived from hematopoietic stem cell (HSC) is a central dogma in hematology. However, exceptions are the fetal hematopoiesis in which primitive and definitive type of erythromyeloid cells are already produced from hemogenic endothelial cells (HECs) ...
2023, Experimental Hematology Citation Excerpt : The elucidation of mechanisms underlying EHT is critical for generating functional HSCs in vitro for clinical applications [90–93]. During EHT, endothelial cells undergo a series of molecular and cellular changes, enabling them to differentiate into HSCs...
pathology hematology and blood bank radiology technician paper-i radiography child, old age & health care services paper-i old age care opthalmic technician paper-i common ocular disease, special investigation and o.t. procedure catering and food technology group food products technology paper-i ...
11.hsc的分类可以将造血干细胞库细分成三个主要组:(1)短期hsc,其能够产生分化细胞的克隆仅4-6周;(2)中期hsc,其能够在变得消失之前维持分化细胞后代6-8个月;和(3)长期hsc,其能够无限地维持血细胞生成(testa u. annals of hematology (2011) 90(3): 245-271)。
2010, Experimental Hematology Citation Excerpt : Donor mice were also injected SC with TS (400 mg/kg), G-CSF (4 × 100 μg/kg, once per day, 24 hours apart) or vehicle. AMD3100 is a small molecule that inhibits the chemokine CXC receptor-4 and stromal derived factor-1 (also called...
[0015]可以将造血干细胞库细分成三个主要组:(1)短期HSC, 其能够产生分化细胞的克隆仅4‑6周;(2)中期HSC, 其能够在变得消退之前维持分化细胞后代6‑8个月;和(3)长期HSC, 其能够无限地维持血细胞生成(Testa U. Annals of Hematology (2011) 90(3): 245‑271)。 [0016]血细胞生成 [0017]血细胞生成...
Indian Journal of Hematology and Blood Transfusion (2023)Associated content Nature Outlook Sickle-cell disease Sections Figures References Abstract References Acknowledgements Author information Ethics declarations Additional information Rights and permissions About this article This article is cited by Advertiseme...
- 《Pediatric Hematology & Oncology》 被引量: 56发表: 2010年 Effect of stem cell mobilization with cyclophosphamide plus granulocyte colony-stimulating factor on morphology of haematopoietic organs in mice Hematopoietic Stem CellsCyclophosphamideImmunosuppressive AgentsKi-67 AntigenBoth granulocyte colony-...
State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China Lu Wang State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences...