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PGC-1α directly interacts with class IIa HDACs; selective inhibitors increased PGC-1α protein in muscles. Hsc70 deacetylation by HDAC4 affects its chaperone activity. Through these endogenous HDAC4 substrates, we identified several muscle metabolic pathways that are regulated by class IIa HDACs, ...
We identified Hsc70 T265 as a CCV class specific phosphorylated Hsc70 residue by its ability to bind CaM/Ca2+ if it is not phosphorylated. Formation of this complex will prevent Hsc70 homodimerization and thus its clathrin disociation activity. We compared the amounts of 12 kinases and of ...
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Capillary electrophoresis (CE) provides a convenient method for the analysis of PAAP/DNA hybrids of the present invention. A number of review articles and books provide an introduction to principles and applications of capillary electrophoresis (Monnig, et al., 1994, Grossman and Colburn, 1992, Chr...