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OTUD4 is a deubiquitination enzyme implicated in cancer biology but remains poorly characterized. While some studies suggest that OTUD4 functions as a tumor suppressor, it is widely regarded as an oncogene.39,41,42,43,44 Further investigation of OTUD4-interacting proteins and downstream targets ...
Cohesin subunit RAD21: From biology to disease 2020, Gene Show abstract Clonal hematopoiesis: mechanisms driving dominance of stem cell clones 2020, Blood Show abstract ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinstag1 from WAPL 2020, eLife Show abstract Subtype-spec...
This transplant protocol has been very useful for subsequent stem cell biology studies. See also Traver et al., 4 Nature Immunol. 1238-46 (2003). Limiting-dilution analyses of zebrafish whole kidney marrow (WKM) cells may show the frequency of HSCs in zebrafish kidney marrow. Because these ...
The biology of chronic graft-versus-host disease: a Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant. 2017;23:211–34. Article PubMed Google Scholar Hatzimichael...
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2024, Nature Cell Biology Histone modifications in drug-resistant cancers: From a cancer stem cell and immune evasion perspective 2023, Experimental and Molecular Medicine Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer 2023, Cellular...