目的探讨环状RNAhsa_circ_0001946在乳腺癌组织中的表达情况及hsa_circ_0001946/miR-7/Kruppel样因子4(KLF4)轴调控乳腺癌细胞发生侵袭和转移的机制。方法收集2018年6月至2019年8月在温州医科大学附属第三医院切除的乳腺癌组织标本及其癌旁正常乳腺组织标本91例。采用实时荧光定量PCR法检测乳腺癌及其癌旁正常组织中hsa_...
circ-CDR1asmicroRNA spongeExperimental analysis of circular RNA in intervertebral disk degeneration (IDD).#This study aimed to explore the roles of hsa_circ_0001946 (circ-CDR1as) in mechanical stress-induced nucleus pulposus cell injury in IDD.#Mechanical stress is an important pathogenic factor for...
外周血淋巴细胞中hsa_circ_0001946高表达也是高血压患病的危险因素(OR=4.130,95%CI 1.851~9.214),而hsa_circ_0125589与高血压患病无相关性.超重/肥胖与hsa_circ_0001946高表达同时存在时患高血压的风险是非超重/肥胖且hsa_circ_0001946低表达的13.121倍(95%CI 3.893~44.231).焦虑与hsa_circ_0001946高表达同时存在...
Conclusion The present work demonstrated the predictive power of hsa_circ_0001946, hsa-miR-7-5p and PARP1 as combined biomarkers for CHD, and suggests a regulatory axis they consisted might contribute to the CHD development.doi:10.1016/j.ijcard.2020.12.026Shuna Huang...
外周血淋巴细胞中hsa_circ_0001946高表达也是高血压患病的危险因素(OR=4.130,95%CI 1.851~9.214),而hsa_circ_0125589与高血压患病无相关性.超重/肥胖与hsa_circ_0001946高表达同时存在时患高血压的风险是非超重/肥胖且hsa_circ_0001946低表达的13.121倍(95%CI 3.893~44.231).焦虑与hsa_circ_0001946高表达同时存在...
Comment on: Association study of hsa_circ_0001946, hsa-miR-7-5p and PARP1 in coronary atherosclerotic heart disease - ScienceDirectShimao Ni aXiaofei Li bInternational Journal of Cardiology