Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity. J. Pathol. 2012, 226, 108-119. [CrossRef] [PubMed]Giricz, O.; Reynolds, P.A.; Ramnauth, A.; Liu, C.; Wang, T.; Stead, L.; Childs, G.; Rohan, T.; Shapiro,...
Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity. J. Pathol. 2012, 226, 108-119. [CrossRef] [PubMed]Giricz O, Reynolds PA, Ramnauth A, Liu C, Wang T, Stead L, Childs G, Rohan T, Shapiro N, Fineberg S, Kenny PA...
We conclude that hsa-miR-375 and hsa-miR-133a-3p may serve as new markers of rectal or colon cancer and should be further investigated to search for different etiologies of colorectal cancer. 展开 关键词: differential expression, colorectal cancers, Illumina sequencing, matched tumor and normal ...
hsa-miR-375和hsa-miR-183-5p表达显著降低(p<0.05);hsa-miR-375和hsa-miR-183-5p过表达质粒转染HEC-1B后,细胞增殖能力明显降低,细胞凋亡百分比提高,TP53,Bax的mRNA表达水平显著提高,Bcl-2的mRNA表达水平显著降低(p<0.05).研究结果表明,hsa-miR-375和hsa-miR-183-5p可通过调控凋亡相关基因的表达促进HEC-1B...
DATA SHEET Hsa-miR-375 ProbeFremontTel
Hsa-miR-375 promotes the progression of inflammatory bowel disease by upregulating TLR4WU, C.-P.BI, Y.-J.LIU, D.-M.WANG, L.-Y.European Review for Medical & Pharmacological Sciences
miR-375Reactive oxygen speciesNOX4Decidualization of the endometrial stromal cells (ESCs) is essential for successful embryo implantation. It involves the transformation of fibroblastic cells into epithelial-like cells that secrete cytokines, growth factors, and proteins necessary for implantation. Previous...
A method for promoting the expression of proteins comprises the step of treating the cell line with endorphin and reducing the expression level of hsa-miR-375. The proteins are solute carrier family 16-member 2 (monocarboxylic acid transporter 8), ELAV (embryonic lethal-abnormal vision-Drosophila)...
JAK 2 was identified as a downstream mRNA target of miR‐375 by RNA pull‐down and dual‐luciferase reporter gene assays, its expression in HCC cell lines were positively regulated by hsa_circ_101280 and negatively by miR‐375 expression. Furthermore, the silencing of hsa_circ_101280 ...
Mechanistically, we confirmed that hsa_circ_0136666 competitively upregulated PRKDC expression by sponging miR-375-3p, regulating immune checkpoint proteins, prompting phosphorylation of PD-L1 to preventing its degradation, driving PD-L1 aggregation and suppressing immune function, thereby impairing cancer ...