HUB基因中仅ESR1在HCC中低表达,并对HCC患者的生存预后有显著意义,且ESR1 mRNA 3'UTR直接与hsa-miR-106b-5p结合;Logistic回归分析发现低表达的ESR1是HCC患者生存预后的独立危险因素;且所构建的风险预测模型具有较好的准确性和有效性.结论hsa-miR-106b-5p调控ESR1使其在HCC中低表达,且不利于HCC患者的生存预后,可...
hsa-mir-106b RT-PCR检测和U6校准试剂盒 英文名称: hsa-mir-106b RT-PCR Detection and U6 Calibration Kit 品牌: Abbexa 货号: abx096467 规格: 50 rxns 价格: $464 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 试剂和工具 试剂...
Mechanically, we found that hsa_circ_000984 may act as a competing endogenous RNA (ceRNA) by competitively binding miR-106b and effectively upregulate the expression ofCDK6, thereby inducing a series of malignant phenotypes of tumor cells. Taken together, these observations suggest that the hsa_...
摘要: 目的Hsa-miR-106b-25簇涉及肿瘤的多种生物学过程,文中对hsa-miR-106b-25簇:miR-106b、miR-93、miR-25进行靶基因的预测及功能分析,为进一步研究这3个miRNAs的功能及他们之间的相互作用调节机制提供线索. 方法 应用miRBase数据库获取miR-106 b、miR-93及... 查看全部>> ...
目的:探讨hsa-miR-199a-5p在缺血性脑卒中(IS)患者血清中的表达和意义.方法:收集118例IS患者及125例健康人群的血清标本.通过实时荧光定量PCR(q PCR)检测血清hsa-miR-199a-5p的表达,用ROC曲线分析hsa-miR-199a-5p表达应用于诊断IS的价值,并对hsa-miR-199a-5p表达与研究人群的临床特征进行相关性分析.结果:hsa...
These genes were miR-224-3p, miR-4762-5p, circ_0016956, circ_0006841, circ_0006635, circ_0056281, circ_0005223, circ_0005777, FZD1, KLF10. Among them, we focused on the downregulated mRNAs (FZD1 and KLF10) significantly correlated with overall survival in GBM. It has been reported in ...
International Journal of Molecular Sciences Article LncRNA RP11-79H23.3 Functions as a Competing Endogenous RNA to Regulate PTEN Expression through Sponging hsa-miR-107 in the Development of Bladder Cancer Hong Chi 1, Rui Yang 1, Xiaying Zheng 1, Luyu Zhang 2, Rong Jiang 3 and Junxia Chen ...
BMC Medical Genomics (2023) 16:21 https://doi.org/10.1186/s12920-023-01450-w BMC Medical Genomics RESEARCH Open Access FZD1/KLF10‑hsa‑miR‑4762‑5p/ miR‑224‑3p‑circular RNAs axis as prognostic biomarkers and therapeutic targets for glioblastoma: a comprehensive report ...
miR-106b 在克罗恩病(Crohn's disease,CD)中的表达及其与自噬的关系,为 CD 的 分子诊断和靶向治疗提供新思路.方法:在环状 RNA 芯片检测的基础上,收集活动期 CD 患者及健康体检者各 40 例,采用实时定量 PCR 检测肠黏膜组织中 hsa circ 0023397 和 miR-106b 的表达情况,并用 Western Blot 检测自噬相关蛋白 ...
hsa‐miR‐106b‐5p participates in the development of chronic thromboembolic pulmonary hypertension via targeting matrix metalloproteinase 2doi:10.1177/2045894020928300Miao, RanDong, XingbeiGong, JuanniWang, YingGuo, XiaojuanLi, YidanLiu, MinWan, Jun...