HPV病毒只有8个编码基因。其中E6和E7基因可在高度恶性肿瘤和宫颈癌组织中表达,E6、E7基因编码的E6、E7蛋白引起宫颈上皮细胞转化,能够促使细胞恶变,是HPV致癌基因。E6和E7癌蛋白能够调控细胞周期,使正在分化的宿主角质化细胞处在一个适合病毒基因复制扩增以及晚期基因表达的阶段。E6可通过促进p53过早降解而抑制p53的功能...
普健生物作为AntibodySystem在亚洲区授权总代理,携手法国ProteoGenix,为亚洲广大科研工作者提供优质的科研产品。 AntibodySystem关于HPV病毒抗原产品展示 Catalog No:YVV08801Name:Recombinant Human papillomavirus type 16/HPV16 L1/Major capsid protein L1 Protein, N-GST & C-HisPredicted molecular weight:84.36 kDaExpre...
HPV病毒只有8个编码基因。其中E6和E7基因可在高度恶性肿瘤和宫颈癌组织中表达,E6、E7基因编码的E6、E7蛋白引起宫颈上皮细胞转化,能够促使细胞恶变,是HPV致癌基因。E6和E7癌蛋白能够调控细胞周期,使正在分化的宿主角质化细胞处在一个适合病毒基因复制扩增以及晚期基因表达的阶段。E6可通过促进p53过早降解而抑制p53的功能...
Polyclonal 类型 Antibody 抗原 Papillomavirus native protein 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型 IgG fraction 保存液 PBS, pH 7.2 内含物 0.1% sodium azide 保存条件 Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. ...
HPV 6-L1 Polyclonal Antibody (Screening Kit) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
Polyclonal Immunogen E. coli - derived recombinant HPV52 E6/Protein E6 (Met1-Val148). Tested applications ELISA: 1:4000-1:8000, WB: 1:1000-1:4000 Target Protein E6, E6 Concentration 0.57 mg/ml Purification Purified by antigen affinity column. Applications ELISA, IHC, WB Form Liq...
The p53 protein was detected using the anti-p53 (DO-1) mouse monoclonal antibody (sc-126, Santa Cruz Biotechnology), and the loading control alpha-actinin was detected using the rabbit anti-alpha-actinin (H-300) polyclonal antibody (sc-15335, Santa Cruz Biotechnology). Western blots were ...
(HVR). The insertion or substitution of aa 12–41 of L2 HPV-16 within HVR1 or HVR5 resulted in the creation of recombinant ad5. The specific L2 response to the recombinant ad5 was initially weak; however, the incorporation of alum and MPL adjuvants augmented antibody titers. NAb titers ...
et al. Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology. Cell 163, 988–998 (2015). Article CAS PubMed PubMed Central Google Scholar Gunn, B. M. & Alter, G. Modulating antibody functionality in infectious disease and vaccination. Trends Mol. Med. 22,...
CAR T cells are designed to express receptors that redirect polyclonal T cells to surface-exposed tumour-associated antigens (TAAs) for subsequent tumour elimination [142]. A phase I/II study is currently recruiting participants to assess the feasibility, safety and efficacy of CAR T cells in ...