We therefore evaluated the clinical utility of a novel dual biomarker-based approach (p16/Ki-67 Dual-stained cytology) for the identification of CIN2+ in women with Pap negative/HPV positive screening results, without the need to refer all women to immediate colposcopy. Methods All women aged ...
[2] Jason D Wright, MD.宫颈上皮内瘤变:专业术语、发病率、发病机制和预防.UpToDate 2021. [3] Katki HA, Schiffman M, Castle PE, et al. Five-year risks of CIN 3+ and cervical cancer among women who test Pap-negative but are HPV-positive...
2019年9月18日,在国外细胞病理学最著名杂志《Cancer Cytopathology》上,陶祥博士等人线上提前发表了其最新研究 “Prevalence of HPV-16/18 Genotypes and Immediate Histopathologic Correlation Results in a Chinese Population With Negative Cyt...
study.HPV primary testing within population-based organised cervical cancer screening programmes.Italian women enrolled in seven pilot projects and attending the second round.On the basis of the cytology triage performed on HPV-positive women, immediate colposcopy or HPV repeat at 12months was ...
For primary HPV screening, all HPV positive results need additional triage, but the management of HPV positive women with negative cytology is particularly challenging, since the risk in this group is too high to return women to regular screening, but too low for colposcopy referral [15], [24...
HPV16/18 detection may improve cervical cancer risk stratification and better guide which HPV-positive women warrant immediate colposcopy/biopsy. We estimated risks of cervical precancer and cancer by HPV genotype and cytology during the implementation phase of primary HPV testing in Norway. Methods A...
This randomised study compared the detection rate of cervical intraepithelial neoplasia-positive (CIN2+) based on histology in women performing repeated self-sampling of vaginal fluid (VF) for human papillomavirus (HPV) test with a control group following the ordinary screening by Pap smear cytology....
The overall hrHPV-positive rate was 14.9% (25,507 of 171,273) in the women with negative cytology. Among the 18,423 cytology-negative, HPV-positive cases tested with the Cobas assay, the overall HPV-16/18 prevalence was 24.7%, with 17.9% being HPV-16–positive, 6.2% being HPV-18–...
展开更多 Objective:This study aims to explore the predictive value of p16/Ki-67 in the progression of high-risk HPV-positive patients with negative cytology.Methods:One hundred and sixty-eight high-risk HPV-positive women with negative cytology were enrolled from May 2017 to Jun...MORE 作者 ...
Conclusions Both HIV-positive and negative women presented a significant reduction in HPV infection during the postpartum period. HIV-positive status was found to be associated with a longer period of time to clear HPV infection in pregnant women.Peer...