OBJECTIVE:Human papillomavirus (HPV) 16/18 genotyping is an effective method for triage of high-risk (hr) HPV-positive women in primary hrHPV screening for cervical cancer. The present study aimed to evaluate whether co-infected with other hrHPV types will affect the risk of cervical carcinogene...
Conclusion: In conclusion, we found that while HPV other types were positive in two thirds of the patients, HPV 16 and/or 18 were positive in more than four fifths of the cancer cases. In the high-risk HPV positive patient group, HPV type can be used as a criterion ...
The Cobas4800 assay is an FDA-approved real-time PCR-based HPV test that can provide both partial genotyping and cycle threshold values (CtV) for HPV- positive channels. The assay reports 14 high-risk HPV types in three channels: HPV16, HPV18, and a pooled 12 other hrHPV types (HPV-31...
This test uses a cocktail probe to detect 13 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68. Samples with HC2 outcome of ⩾1 RLU/CO were considered as hrHPV positive. HC2-positive samples were tested with GP5+/6+-PCR-EIA (Jacobs et al, ...
rate of hrHPV was other types of hrHPV > HPV18 > HPV16. The positive rate of TCT was 6.5% (716/11 046), in which ASC-US, LSIL, ASC-H, HSIL, SCC and AGC were 4.5%, 0.6%, 0.8%, 0.4%, 0.1% and 0....
Upon comparison with HPV-positive women with normal cytology, PRs for women with ICC were 6.5 (95% CI: 4.5–9.4) for HPV16 and 6.7 (95% CI: 3.8-12.1) for HPV16/18/31/33/45/52/58, but did not exceed one for any other HR HPV types. Possible HR, LR and multiple-type infections ...
Of 7,694 participants, 53.6% (95% CI 51.4–55.8) were positive for any HPV type. The prevalence of high-risk HPV types was significantly higher in women (38.6% vs. 29.2%, P < 0·001). The HPV types included in the quadrivalent vaccine were detected in 1002 (14.8%) specimens, ...
4, l). The remaining 4 cases (including 2 cases of HPV-DNA positivity for 16 and 12 other HR-HPV types) were all negative and subsequently revised to inflammatory lesions or reparative changes. For CIN3, 3 cases were negative for HPV-DNA, but both were positive for HR-HPV RNAscope, ...
[5]Guan, P., et al.,Human papillomavirus types in 115,789 HPV-positive women: a meta-analysis from cervical infection to cancer.Int J Cancer, 2012.131(10): p. 2349-59. [6]Chaturvedi, A.K.,Beyond Cervical Cancer: Burden of Other HPV-Related Cancers A...
[5]Guan, P., et al., Human papillomavirus types in 115,789 HPV-positive women: a meta-analysis from cervical infection to cancer. Int J Cancer, 2012. 131(10): p. 2349-59. [6]Chaturvedi, A.K., Beyond Cervical Cancer: Burden of Other HPV-Related Cancers Among Men and Women.Journal...