Psychiatry Res 20:265-273Coryell W, Zimmerman M: HPA-axis abnormalities in psychiatrically well controls. Psychiat Res 1987; 20: 265–273.Coryell, W, Zimmerman, M (1987) HPA-axis abnormalities in psychiatrically well controls. Psychiatry Res 20: pp. 265-273...
下丘脑-垂体-肾上腺轴(Hypothalamic-pituitary-adrenal axis,HPA axis)是应对压力的首要环节,急性或慢性应激都可引起HPA轴的功能发生变化。本文主要针对HPA轴与抑郁症的关联及及其功能失调的分子机制作以下综述。 关键词:抑郁症;HPA轴;分子机制 前言 抑郁症以持久的心境低落为主要特点,并伴随有失眠、悲观厌世、食欲下降...
Holsboer F, Barden N. Antidepressants and hypothalamic-pituitary-adrenocortical regulation. Endocr Rev. 1996;17(2):187-205. Vreeburg SA, Hoogendijk WJ, van Pelt J, et al. Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Arch Gen Psy...
下丘脑-垂体-肾上腺轴(Hypothalamic-pituitary-adrenal axis,HPA axis)是应对压力的首要环节,急性或慢性应激都可引起 HPA轴的功能发生变化。本文主要针对 HPA 轴与抑郁症的关联及及其功能失调的分子机制作以下综述。 关键词:抑郁症;HPA...文档格式:PDF | 页数:1 | 浏览次数:948 | 上传日期:2017-06-08 16:21:...
一、抑郁患者HPA轴功能 与早期的研究结果一致,近来的研究也显示抑郁患者的血浆皮质醇浓度分泌增加,失去了正常人夜间自发性分泌抑制的节律,整天处于肾上腺皮质功能亢进状态[1]。Rubin等(1996)[2]的研究还发现,与健康对照相比,抑郁患者的肾上腺皮质增生约38%,增生的程度与皮质醇的浓度有关;且随着抑郁的恢复,这种增生...
Rearing condition and rh5-HTTLPR interact to influence LHPA-axis response to stress in infant macaques Rear- ing condition and rh5-HTTLPR interact to influence LHPA-axis response to stress in infant macaques. Biol. Psychiatry 55, 733-738.Barr CS, Newman TK, Shannon C, Parker C, Dvoskin RL...
Intense psychosocial stress during early life has a detrimental effect on health-disease balance in later life. Simultaneously, despite its sensitivity to stress, the developing microbiome contributes to long-term health. Following stress exposure, HPA-axis activation regulates the “fight or flight” ...
The Hypothalamic–Pituitary–Adrenal Axis in Bipolar Disorder One of the most consistent findings in biological psychiatry is derangement of the hypothalamic-pituitary-adrenal (HPA) axis in patients with severe mood d... DJ Bond,AH Young 被引量: 278发表: 2007年 Extended report:Genetic variation in...
Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder[J].Br J Psychiatry,2004,184:496-502. [本文引用:0] [23] WATSON S,GALLAGHER P,SMITH M S,et al.The dex /CRH test is it better than the DST?[J].Psychoneuroendocrinology,2006,31(7): 889-894. DOI:10.1016/j...
Basal hypothalamic pituitary adrenal axis activity and hippocampal volumes: the SMART-Medea study. Biol Psychiatry 67: 1191–1198. Article Google Scholar Kuningas M, de Rijk RH, Westendorp RG, Jolles J, Slagboom PE, van HD (2007). Mental performance in old age dependent on cortisol and ...