The distinct HOX gene family members we have revealed, differ to those related to melanoma development and positioning, as such we propose that these may contribute to the positioning of acquired melanocytic nevi, and in combination with common somatic alterations in BRAF, may contribute to nevus ...
The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. EMBO J. 1989 ;8(5):1497-505 4. Graham A, Papalopulu N, Krumlauf R. The murine and Drosophila homeobox gene complexes have common features of organization and expression. ...
Like other HOX gene family members, HOXB13 expression is generally restricted to undifferentiated and/or proliferating cells during embryogenesis [11]. However, dysregulated expression of HOXB13 has been described in endocrine-responsive tumors that include prostate, ovarian, endometrial and breast ...
Hox gene family Hox gene family Hox genes HOX transcript antisense RNA Hox-1.4-like protein Hox-1.5-like protein HOX1 HOX1.3 HOX1.7 HOX1.8 HOX10 HOX12 HOX1D HOX1E HOX1F HOX1G HOX1H HOX1I HOX1K HOX4I HOXA1 HOXA10 HOXA10 HOXA10 HOXA10 HOXA11 HOXA2 HOXA3 HOXA4 HOXA5 HOXA6 HOX...
The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.This paper reports the cloning of the fourth major murine homeogene complex, HOX-5. The partial characterization of this gene cluster revealed the presence of two novel genes (Hox-...
The ancestral roles of Hox genes, a family of transcription factors with evolutionarily conserved functions in embryonic head to tail patterning, are tightly linked to the emergence of segmented animal body plans4,5. Additionally, Hox gene functions in neuronal development throughout taxa suggest poten...
Receiver operating characteristic (ROC) statistical method curve showed that the expression level of seven members of HOX gene family can distinguish tumor from nontumor tissue. Correlation analysis of clinical and gene expression data revealed that HOXC8 and HOXD11 genes were associated with the ...
Background. The homeobox (HOX) gene family has been found to be involved in human cancers. However, its involvement in hepatocellular carcinoma (HCC) has not been well documented. Here, we comprehens...
Given our phylogenetic data, we compared the topologies of those paralogous genes of the each gene family which have arisen within the time window of vertebrates-invertebrates and tetrapods-fishes divergence to test which genes have duplicated concurrently with each other and with the linked HOX ...
基因简称(symbol) HOXC13 [HGNC] [GeneCards] [NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) 基因家族代码(gene_family_id) 518 [HGNC] [GenScript] omim代码 142976 entrez码 3229 [Vega] ensembl基因码 ENSG00000123364 [Ensembl] 基因家族(gene family) HOXL ...