called pathogen-associated molecular patterns (PAMPs), such as nucleic acid structures, lipoteichoic acid, and peptidoglycan [12]. The pattern recognition receptors (PRRs) of immune cells include, in addition to TLRs, the NOD-like receptors (NLRs) and the RIG-1-like receptors (RLRs), which are...
Successful clinical use of DNA vaccines may require combined employment of all of these parameters, and combination treatment with additional drugs. Keywords: DNA vaccine; nano carrier; promotor; transgene; adjuvant; antigen presenting cells; dendritic cell; macrophage 1. Introduction Compared to ...
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