The survival benefit conferred by this agent, along with its marked efficacy with regard to spleen volume and symptom reduction, have made ruxolitinib the cornerstone...doi:10.1097/01.COT.0000514187.87553.3aBose, PrithvirajVerstovsek, Srdan
Advanced systemic mastocytosis (SM) is a rare myeloid neoplasm characterized by uncontrolled accumulation of neoplastic mast cells (MCs) in various organs with consecutive impairment of organ function, drug resistance, and a poor prognosis. Advanced SM may present as smoldering or slowly progressing ne...
When to Suspect and How to Diagnose and Treat Pediatric Cutaneous and Systemic MastocytosisCarterAaaai
How to diagnose and treat mastocytosis: the predominant presentation of this mast-cell disorder is development of pruritic lesions--especially after rubbing or exposure to heat.(FEATURE)Weinberg, Jeffrey M
Advanced systemic mastocytosis—Revised classification, new drugs and how we treatdoi:10.1111/bjh.19245WORLD Health OrganizationMAST cell diseaseMAST cellsNOSOLOGYPROTEIN-tyrosine kinase inhibitorsCELL proliferationDRUGSSummary: Mastocytosis constitutes the neoplastic proliferation of mast cells and ...
Valent P., Sperr W.R., Akin C. How I treat patients with advanced systemic mastocytosis. Blood 2010; 116 (26): 5812--5817.Valent P, Sperr WR, Akin C: How I treat patients with advanced systemic mastocytosis. Blood 2010, 116:5812-5817....