Pseudothrombocytopeniais term given to situations in which there is a falsely low platelet count on the blood smear reviewed by the laboratory. This can happen because of occasional clumping of the platelets together when the blood is drawn. Therefore, small number of individual platelets may be s...
How I treat type 2B von Willebrand disease Type 2B von Willebrand disease (VWD) is an inherited bleeding disorder caused by changes in von Willebrand factor (VWF) that enhance binding of VWF to GPIb on platelets. Although this disorder is seemingly well defined because of this si... R Kruse...
Blood thinners.If you start taking ablood thinneror another drug (likeaspirin) that makes it harder for your blood to clot, you may get more bruises than you’ve had in the past. This is because every time you bump into something, if you happen to break any small blood vessels beneath ...
Selective serotonin reuptake inhibitors (SSRIs) are common drugs used to treat anxiety, depression, and other mood disorders. However, SSRIs don’t work in up to 40% of people who use them. This may be because the brain isn’t producing enough serotonin, or that there are too few seroton...
Macrophages can process phagocytosed platelets and present autoantigens to T helper (Th) cells, which dictate the proliferation of B cells into autoantibody-secreting plasma cells, thus constituting a continuous autoantigen feedback loop [25, 26]. Decreased expression of the inhibitory FcγR on ...
a bleeding disorder, or low levels of platelets in your blood; kidney disease (or if you are on dialysis); diabetes (unless you are taking pregabalin to treat diabetic neuropathy); drug or alcohol addiction; or a severe allergic reaction (angioedema).Do...
You should not use Exjade if you are allergic to deferasirox, or if you have: severe liver or kidney disease; advanced cancer; a bone marrow disorder; or low levels of platelets in your blood. Tell your doctor if you have ever had: ...
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When you havepolycythemia vera, your body makes too many redblood cells. You might have extra white blood cells and platelets, too. The condition is also known as polycythemia rubra vera, primary polycythemia, and Osler-Vaquez disease.
The underlying mechanisms of harm reported in randomized trials may be related to the role of platelets beyond hemostasis, including mediating inflammation. Research supports the implementation of a restrictive platelet transfusion policy. Research is needed to better understand the impact of platelet ...