HER2-positiveNode-negativeBreast cancerChemotherapyTrastuzumabSmall (pT1a-b), node-negative (pN0) breast cancer generally has a good prognosis. However, HER2-positive status is associated with an increased risk of relapse and decreased survival even in these tumors. Although there are only few data...
“We've completely flipped the outcomes for HER2-positive breast cancer, where it has gone from one of the most feared types of breast cancer to one of the most successfully treated types of breast cancer.”—Harold Burstein by Peter Attia November 6, 2023 Read Time 69 minutesHarold...
Patients with oestrogen receptor positive (ER+) breast cancer (80% of all breast cancers) have a continued risk of their cancer recurring for many years or even decades after their original diagnosis and surgery. To reduce their risk of relapse, patients undergo five to 10 years of hormone th...
Human epidermal growth factor receptor 2 (HER2) is a protein that can be expressed on the surface of some breast cancer cells.Breast cancerthat expresses HER2 is known asHER2-positiveand HER2-low depending on how many HER2 proteins are on the cells. These types of breast cancer may be able...
Kisqali (ribociclib)is a medicine used for certain types ofbreast cancer. Kisqali is used to treat breast cancer that ishormone receptor (HR)-positiveandhuman epidermal growth factor receptor 2 (HER2)-negative. It can be used to treat breast cancer that is advanced or has spread to other ...
Management requires combined modality therapy, including neoadjuvant chemotherapy with an anthracycline and taxane-based regimen, followed by surgery and radiotherapy, plus concurrent anti-HER2 therapy for HER2-positive disease, and endocrine therapy for at least 5聽years after surgery for estrogen-receptor...
Approximately 20 percent of breast cancers are HER2+, meaning they over-express the HER2 gene, resulting in a particularly aggressive form of the disease.4 The first targeted treatment approved to treat HER2+ breast cancer was Herceptin® (trastuzumab) “” in which the BCRP provide...
One of the most significant applications of mAbs is in oncology. These antibodies have revolutionized cancer treatment by directly targeting cancer cells or blocking the signals that promote their growth. Examples include trastuzumab, used to treat HER2-positive breast cancer, and rituximab, u...
Foods to eat and avoid for HER2+ patients and survivorsFoods to eat and avoid for inflammatory breast cancer patients & survivorsAll breast cancer patients should take into account their ER/PR subtype in designing their diets:Hormone receptor positive (ER+/PR+) breast cancer...
These treatments are currently being used to manage common cancers such aslung, breast,colorectal,stomach,liver,melanoma, certain types of leukemia andlymphoma, and many others. For example, patients with HER2 (human epidermal growth factor receptor 2) positive bre...