The present disclosure provides a method of treating a reversible hemophilia arthropathy of the joints in humans with hemophilia, including administering administering an effective amount of a chimeric protein or composition comprising a coagulation factor and an Fc region to the human.ジェニファーデ...
Treatment With Replacement TherapyThe main treatment for hemophilia is called replacement therapy. Concentrates of clotting factor VIII (for hemophilia A) or clotting factor IX (for hemophilia B) are slowly dripped or injected into a vein. These infusion
How we choose factor VIII to treat hemophilia In high-income countries, the large availability of coagulation factors for replacement therapy of patients with hemophilia A has raised the life expectanc... PM Mannucci,ME Mancuso,E Santagostino - 《Blood》 被引量: 83发表: 2012年 How we choose...
Johnny N.Bujan, WillemTrask, PeterCallaghan, Michael U.Young, GuyAsikanius, ElinaPeyvandi, FloraSantagostino, ElenaKruse-Jarres, RebeccaNegrier, ClaudeKessler, CraigXu, JinWindyga, JerzyShima, Midorivon Mackensen, Sylvia - 《Haemophilia the Official Journal of the World Federation of Hemophilia》...
Having a health condition.Some diseases can make you more likely to bruise: Blood-clotting disorder.If you have a blood clotting disorder such ashemophilia, you’re more likely to bruise than someone without the condition. If your blood takes a long time to clot, then more blood will pool ...
Hemophilia is a bleeding disorder with X-linked inheritance. Current prenatal diagnostic methods for hemophilia are invasive and pose a risk to the fetus. ... KC Chan,TY Leung,G Mellars,... 被引量: 0发表: 2013年 Correction: Marques, A. et al. Evolution of Plant B Chromosome Enriched Se...
Factor VIIIa brings 2 other proteins (factor IXa and factor X) together, allowing the blood coagulation process to continue, stopping a bleed. How hemophilia A affects coagulation Blood coagulation process can’t continue normally In people with hemophilia A who have low or missing factor VIII, ...
Plasma (fresh frozen plasma), once thawed, is transfused to treat bleeding disorders when many clotting factors are missing. This occurs in liver failure, when too much of a blood thinner called Coumadin has been given, or when severe bleeding and massive transfusions result in low levels of...
PCCs (products made from pooled human plasma) were initially developed to treat hemophilia. They can be infused rapidly and generally reverse anticoagulation three to five times faster than fresh frozen plasma, which must be thawed. Recombinant Activated Factor VII (Factor rVIIa), while approved in...
Blood disorder including anemia or hemophilia Any dysfunction of the immune system Abnormal blood work It’s still unclear as to how lupus is contracted. The disease isn’t contagious. Although it can run in families, only about 20 percent of cases are linked to a parent or sibling with the...